CD01909

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01909

CD01909

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Prdx1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• peroxiredoxin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• thioredoxin peroxidase 2
• proliferation-associated gene A
• osteoblast-specific factor 3
• macrophase stress protein 23 kd
• macrophage 23 kDa stress protein
• thioredoxin-dependent peroxide reductase 2
• peroxiredoxin 1
• macrophage 23 Kd stress protein
• peroxiredoxin-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• TPx-A
• Prx I
• prx1
• Trx dependent peroxide reductase 2
• Tdpx2
• PrdxI
• OSF-3
• thioredoxin dependent peroxide reductase 2
• Paga
• TDX2
• NkefA
• MSP23
• TPxA
• OSF3
• macrophage 23kDa stress protein
• PrxI
• osteoblast specific factor 3
• macrophase stress protein 22kDa
• PAG

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18477

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• peroxiredoxin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99523

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011034

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000028691

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.30929

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=176763

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Juxiang. Cao, et.al., Prdx1 inhibits tumorigenesis via regulating PTEN/AKT activity., The EMBO journal, 2009, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/19369943
• K P. Brady, et.al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis., Genome research, 1997, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9371744
• Jonah R. Riddell, et.al., Peroxiredoxin 1 stimulates secretion of proinflammatory cytokines by binding to TLR4., Journal of immunology (Baltimore, Md. : 1950), 2010, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/20018613
• M. Takenaka, et.al., Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles., Kidney international, 1998, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/9507200
• Hyun Ae. Woo, et.al., Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling., Cell, 2010, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/20178744
• T. Ishii, et.al., Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein., The Journal of biological chemistry, 1993, 268
  http://rdf.ncbi.nlm.nih.gov/pubmed/8360158
• http://rdf.ncbi.nlm.nih.gov/pubmed/19941984
• H. Shau, et.al., Cloning and sequence analysis of candidate human natural killer-enhancing factor genes., Immunogenetics, 1994, 40
  http://rdf.ncbi.nlm.nih.gov/pubmed/8026862
• S. Kawai, et.al., Cloning and characterization of OSF-3, a new member of the MER5 family, expressed in mouse osteoblastic cells., Journal of biochemistry, 1994, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/8089076
• Ye. Yan, et.al., The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox-dependent activation of GDE2., Cell, 2009, 138
  http://rdf.ncbi.nlm.nih.gov/pubmed/19766572

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• erythrocyte homeostasis
  http://purl.obolibrary.org/obo/GO_0034101
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• natural killer cell mediated cytotoxicity
  http://purl.obolibrary.org/obo/GO_0042267
• nuclear euchromatin
  http://purl.obolibrary.org/obo/GO_0005719
• mitochondrial matrix
  http://purl.obolibrary.org/obo/GO_0005759
• peroxisomal matrix
  http://purl.obolibrary.org/obo/GO_0005782
• heme binding
  http://purl.obolibrary.org/obo/GO_0020037
• thioredoxin peroxidase activity
  http://purl.obolibrary.org/obo/GO_0008379
• response to reactive oxygen species
  http://purl.obolibrary.org/obo/GO_0000302
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• peroxiredoxin activity
  http://purl.obolibrary.org/obo/GO_0051920
• regulation of stress-activated MAPK cascade
  http://purl.obolibrary.org/obo/GO_0032872
• response to oxidative stress
  http://purl.obolibrary.org/obo/GO_0006979
• nucleolus
  http://purl.obolibrary.org/obo/GO_0005730
• oxidoreductase activity
  http://purl.obolibrary.org/obo/GO_0016491
• removal of superoxide radicals
  http://purl.obolibrary.org/obo/GO_0019430
• cell proliferation
  http://purl.obolibrary.org/obo/GO_0008283
• antioxidant activity
  http://purl.obolibrary.org/obo/GO_0016209
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• hydrogen peroxide catabolic process
  http://purl.obolibrary.org/obo/GO_0042744
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• peroxidase activity
  http://purl.obolibrary.org/obo/GO_0004601
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• oxidation-reduction process
  http://purl.obolibrary.org/obo/GO_0055114
• regulation of NIK/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_1901222

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04146

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Peroxisome