CD02079

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02079

CD02079

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slc4a4

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier family 4 (anion exchanger), member 4

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• sodium bicarbonate cotransporter
• pancreas sodium bicarbonate cotransporter
• electrogenic sodium bicarbonate cotransporter 1
• Na(+)/HCO3(-) cotransporter
• solute carrier family 4 member 4
• solute carrier family 4 (anion exchanger), member 4
• electrogenic sodium bicarbonate cotransporter NBCe1 variant D
• solute carrier family 4, sodium bicarbonate cotransporter, member 4

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• NBC
• NBC1
• AI835705
• BETA2
• BHF-1
• NeuroD

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/54403

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier family 4 (anion exchanger), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927555

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001197147
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001136260
• https://www.ncbi.nlm.nih.gov/nuccore/NM_018760

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000060961

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.41044

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603345

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Owen J. Tamplin, et.al., Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives., BMC genomics, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18973680
• Dongki. Yang, et.al., IRBIT coordinates epithelial fluid and HCO3- secretion by stimulating the transporters pNBC1 and CFTR in the murine pancreatic duct., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19033647
• Bernardo V. Alvarez, et.al., Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter., Biochemistry, 2003, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/14567693
• N. Abuladze, et.al., Molecular cloning, chromosomal localization, tissue distribution, and functional expression of the human pancreatic sodium bicarbonate cotransporter., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9651366
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• J. Praetorius, et.al., Molecular and functional evidence for electrogenic and electroneutral Na(+)-HCO(3)(-) cotransporters in murine duodenum., American journal of physiology. Gastrointestinal and liver physiology, 2001, 280
  http://rdf.ncbi.nlm.nih.gov/pubmed/11171615
• O. Bachmann, et.al., cAMP-mediated regulation of murine intestinal/pancreatic Na+/HCO3- cotransporter subtype pNBC1., American journal of physiology. Gastrointestinal and liver physiology, 2003, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/12388213
• Rodrigo S. Lacruz, et.al., The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20529845
• Youn-Bae. Kim, et.al., Expression of Na+/HCO3- cotransporter and its role in pH regulation in mouse parotid acinar cells., Biochemical and biophysical research communications, 2003, 304
  http://rdf.ncbi.nlm.nih.gov/pubmed/12727194
• Haoyang. Yu, et.al., Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts., American journal of physiology. Gastrointestinal and liver physiology, 2009, 297
  http://rdf.ncbi.nlm.nih.gov/pubmed/19779011

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• anion transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0008509
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• regulation of pH
  http://purl.obolibrary.org/obo/GO_0006885
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• sodium:bicarbonate symporter activity
  http://purl.obolibrary.org/obo/GO_0008510
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• inorganic anion exchanger activity
  http://purl.obolibrary.org/obo/GO_0005452
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• symporter activity
  http://purl.obolibrary.org/obo/GO_0015293
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• bicarbonate transport
  http://purl.obolibrary.org/obo/GO_0015701
• transporter activity
  http://purl.obolibrary.org/obo/GO_0005215
• sodium ion transport
  http://purl.obolibrary.org/obo/GO_0006814
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• anion transport
  http://purl.obolibrary.org/obo/GO_0006820

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04972
• http://www.genome.jp/dbget-bin/www_bget?map04976
• http://www.genome.jp/dbget-bin/www_bget?map04964

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Proximal tubule bicarbonate reclamation
• Pancreatic secretion
• Bile secretion