CD02408

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02408

CD02408

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Plk2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• polo-like kinase 2 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• serine/threonine-protein kinase PLK2
• serine/threonine-protein kinase SNK
• serum-inducible kinase
• polo-like kinase 2 (Drosophila)
• PLK-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Snk

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/20620

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• polo-like kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1099790

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_152804

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021701

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.380

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=607023

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• James R A. Hutchins, et.al., Systematic analysis of human protein complexes identifies chromosome segregation proteins., Science (New York, N.Y.), 2010, 328
  http://rdf.ncbi.nlm.nih.gov/pubmed/20360068
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Sheng. Ma, et.al., The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB., Molecular cancer research : MCR, 2003, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/12651910
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• D L. Simmons, et.al., Identification of an early-growth-response gene encoding a novel putative protein kinase., Molecular and cellular biology, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1508211
• Kelly J. Inglis, et.al., Polo-like kinase 2 (PLK2) phosphorylates alpha-synuclein at serine 129 in central nervous system., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19004816
• Yun-Yong. Park, et.al., Polo-like kinase 2 gene expression is regulated by the orphan nuclear receptor estrogen receptor-related receptor gamma (ERRgamma)., Biochemical and biophysical research communications, 2007, 362
  http://rdf.ncbi.nlm.nih.gov/pubmed/17706602
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Timothy F. Burns, et.al., Silencing of the novel p53 target gene Snk/Plk2 leads to mitotic catastrophe in paclitaxel (taxol)-exposed cells., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12897130
• Sheng. Ma, et.al., Role of Plk2 (Snk) in mouse development and cell proliferation., Molecular and cellular biology, 2003, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/12972611

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• signal transducer activity
  http://purl.obolibrary.org/obo/GO_0004871
• mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0000278
• G1/S transition of mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0000082
• mitotic spindle organization
  http://purl.obolibrary.org/obo/GO_0007052
• centriole
  http://purl.obolibrary.org/obo/GO_0005814
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• positive regulation of I-kappaB kinase/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_0043123
• regulation of centriole replication
  http://purl.obolibrary.org/obo/GO_0046599
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• centrosome
  http://purl.obolibrary.org/obo/GO_0005813
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName