CD02411

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02411

CD02411

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Csk

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• c-src tyrosine kinase

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• c-src tyrosine kinase
• p50CSK
• C-Src kinase
• tyrosine-protein kinase CSK
• protein-tyrosine kinase MPK-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AW212630

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12988

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• c-src tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:88537

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007783

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000032312

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.470150
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.21974

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=124095

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• H. Sabe, et.al., Molecular cloning and expression of chicken C-terminal Src kinase: lack of stable association with c-Src protein., Proceedings of the National Academy of Sciences of the United States of America, 1992, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/1372437
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Julie. Zikherman, et.al., CD45-Csk phosphatase-kinase titration uncouples basal and inducible T cell receptor signaling during thymic development., Immunity, 2010, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/20346773
• S M. Thomas, et.al., Specific and redundant roles of Src and Fyn in organizing the cytoskeleton., Nature, 1995, 376
  http://rdf.ncbi.nlm.nih.gov/pubmed/7617039
• P. Gilardi-Hebenstreit, et.al., An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain., Oncogene, 1992, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/1281307
• Takuma. Matsubara, et.al., Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/19874196
• Mohammad Aminur. Rahman, et.al., S-nitrosylation at cysteine 498 of c-Src tyrosine kinase regulates nitric oxide-mediated cell invasion., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/19948721
• James R A. Hutchins, et.al., Systematic analysis of human protein complexes identifies chromosome segregation proteins., Science (New York, N.Y.), 2010, 328
  http://rdf.ncbi.nlm.nih.gov/pubmed/20360068
• P M. Brinkley, et.al., Structure and developmental regulation of the murine ctk gene., Gene, 1995, 163
  http://rdf.ncbi.nlm.nih.gov/pubmed/7590263
• E. Armstrong, et.al., The c-src tyrosine kinase (CSK) gene, a potential antioncogene, localizes to human chromosome region 15q23----q25., Cytogenetics and cell genetics, 1992, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/1377109
• S. Nada, et.al., Identification of major tyrosine-phosphorylated proteins in Csk-deficient cells., Oncogene, 1994, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7526315
• M. Kawabuchi, et.al., Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases., Nature, 2000, 404
  http://rdf.ncbi.nlm.nih.gov/pubmed/10801129
• S. Klages, et.al., Ctk: a protein-tyrosine kinase related to Csk that defines an enzyme family., Proceedings of the National Academy of Sciences of the United States of America, 1994, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/7511815

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• positive regulation of MAP kinase activity
  http://purl.obolibrary.org/obo/GO_0043406
• proline-rich region binding
  http://purl.obolibrary.org/obo/GO_0070064
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• negative regulation of bone resorption
  http://purl.obolibrary.org/obo/GO_0045779
• regulation of Fc receptor mediated stimulatory signaling pathway
  http://purl.obolibrary.org/obo/GO_0060368
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• centrosome
  http://purl.obolibrary.org/obo/GO_0005813
• protein phosphatase binding
  http://purl.obolibrary.org/obo/GO_0019903
• cellular response to peptide hormone stimulus
  http://purl.obolibrary.org/obo/GO_0071375
• intracellular membrane-bounded organelle
  http://purl.obolibrary.org/obo/GO_0043231
• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• regulation of T cell activation
  http://purl.obolibrary.org/obo/GO_0050863
• negative regulation of ERK1 and ERK2 cascade
  http://purl.obolibrary.org/obo/GO_0070373
• protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004713
• negative regulation of low-density lipoprotein particle clearance
  http://purl.obolibrary.org/obo/GO_0010989
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• negative regulation of phagocytosis
  http://purl.obolibrary.org/obo/GO_0050765
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• negative regulation of interleukin-6 production
  http://purl.obolibrary.org/obo/GO_0032715
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• negative regulation of kinase activity
  http://purl.obolibrary.org/obo/GO_0033673
• non-membrane spanning protein tyrosine kinase activity
  http://purl.obolibrary.org/obo/GO_0004715
• cell-cell junction
  http://purl.obolibrary.org/obo/GO_0005911
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName