CD02474

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02474

CD02474

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Man2a1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• mannosidase 2, alpha 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• alpha-mannosidase 2
• mannosidase 2, alpha 1
• golgi alpha-mannosidase II
• AMan II
• mannosidase alpha class 2A member 1
• man II
• mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Map-2
• Mana-2
• Mana2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17158

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• mannosidase 2, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104669

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008549

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024085

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2433

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=154582

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• J. Schneikert, et.al., Two naturally occurring mouse alpha-1,2-mannosidase IB cDNA clones differ in three point mutations. Mutation of Phe592 to Ser592 is sufficient to abolish enzyme activity., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7629073
• C. Antony, et.al., Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle., The Journal of cell biology, 1995, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/7642711
• Tomoya O. Akama, et.al., Essential and mutually compensatory roles of {alpha}-mannosidase II and {alpha}-mannosidase IIx in N-glycan processing in vivo in mice., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16754854
• Ryan S. Green, et.al., Mammalian N-glycan branching protects against innate immune self-recognition and inflammation in autoimmune disease pathogenesis., Immunity, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17681821
• K W. Moremen, et.al., Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans., The Journal of cell biology, 1991, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/1757461
• M. Dizik, et.al., A gene apparently determining the extent of sialylation of lysosomal alpha-mannosidase in mouse liver., Biochemical genetics, 1977, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/849251
• J. Klein, et.al., H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17., Immunogenetics, 1982, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/6816725
• Tomoya O. Akama, et.al., N-Glycan structure analysis using lectins and an alpha-mannosidase activity assay., Methods in enzymology, 2006, 416
  http://rdf.ncbi.nlm.nih.gov/pubmed/17113875
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• respiratory gaseous exchange
  http://purl.obolibrary.org/obo/GO_0007585
• hydrolase activity, hydrolyzing N-glycosyl compounds
  http://purl.obolibrary.org/obo/GO_0016799
• mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity
  http://purl.obolibrary.org/obo/GO_0004572
• liver development
  http://purl.obolibrary.org/obo/GO_0001889
• lung alveolus development
  http://purl.obolibrary.org/obo/GO_0048286
• carbohydrate binding
  http://purl.obolibrary.org/obo/GO_0030246
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• hydrolase activity, acting on glycosyl bonds
  http://purl.obolibrary.org/obo/GO_0016798
• in utero embryonic development
  http://purl.obolibrary.org/obo/GO_0001701
• carbohydrate metabolic process
  http://purl.obolibrary.org/obo/GO_0005975
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• hydrolase activity, hydrolyzing O-glycosyl compounds
  http://purl.obolibrary.org/obo/GO_0004553
• alpha-mannosidase activity
  http://purl.obolibrary.org/obo/GO_0004559
• cation binding
  http://purl.obolibrary.org/obo/GO_0043169
• mannose metabolic process
  http://purl.obolibrary.org/obo/GO_0006013
• Golgi membrane
  http://purl.obolibrary.org/obo/GO_0000139
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• mannosidase activity
  http://purl.obolibrary.org/obo/GO_0015923
• mitochondrion organization
  http://purl.obolibrary.org/obo/GO_0007005
• N-glycan processing
  http://purl.obolibrary.org/obo/GO_0006491
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• vacuole organization
  http://purl.obolibrary.org/obo/GO_0007033

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map00510

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• N-Glycan biosynthesis