CD02486

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02486

CD02486

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Notch3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• Notch gene homolog 3 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• Notch gene homolog 3 (Drosophila)
• notch 3
• neurogenic locus notch homolog protein 3

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AW229011

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18131

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• notch 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:99460

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008716

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000038146

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439741

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600276

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Paolo E. Forni, et.al., A role for FE65 in controlling GnRH-1 neurogenesis., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21228158
• Xuesong. Feng, et.al., Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/21068062
• M. Lardelli, et.al., The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium., Mechanisms of development, 1994, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/7918097
• T A. Mitsiadis, et.al., Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate., The Journal of cell biology, 1995, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/7615640
• Yi. Zhang, et.al., Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease., Blood, 2011, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/20870902
• Takeo. Kitamoto, et.al., Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration., Stem cells, 2010, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/20960513
• C. Larsson, et.al., The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation., Genomics, 1994, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/7698746
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• A. Joutel, et.al., Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia., Nature, 1996, 383
  http://rdf.ncbi.nlm.nih.gov/pubmed/8878478
• R. Williams, et.al., Complementary and combinatorial patterns of Notch gene family expression during early mouse development., Mechanisms of development, 1995, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/8645602

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• calcium ion binding
  http://purl.obolibrary.org/obo/GO_0005509
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• neuron fate commitment
  http://purl.obolibrary.org/obo/GO_0048663
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• Notch signaling pathway
  http://purl.obolibrary.org/obo/GO_0007219
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• negative regulation of cell differentiation
  http://purl.obolibrary.org/obo/GO_0045596
• regulation of developmental process
  http://purl.obolibrary.org/obo/GO_0050793
• positive regulation of smooth muscle cell proliferation
  http://purl.obolibrary.org/obo/GO_0048661
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• forebrain development
  http://purl.obolibrary.org/obo/GO_0030900
• negative regulation of neuron differentiation
  http://purl.obolibrary.org/obo/GO_0045665
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04330
• http://www.genome.jp/dbget-bin/www_bget?map04320

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Dorso-ventral axis formation
• Notch signaling pathway