CD02646

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02646

CD02646

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ramp1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• receptor (calcitonin) activity modifying protein 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• receptor (calcitonin) activity modifying protein 1
• receptor activity-modifying protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 9130218E19Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/51801

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• receptor (calcitonin) activity modifying protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858418

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001168392
• https://www.ncbi.nlm.nih.gov/nuccore/NM_178401
• https://www.ncbi.nlm.nih.gov/nuccore/NM_016894

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000034353

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.3272

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605153

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• C. Derst, et.al., Genomic structure and chromosome mapping of human and mouse RAMP genes., Cytogenetics and cell genetics, 2000, 90
  http://rdf.ncbi.nlm.nih.gov/pubmed/11060459
• John J. Mallee, et.al., Receptor activity-modifying protein 1 determines the species selectivity of non-peptide CGRP receptor antagonists., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11847213
• Juan J. Miret, et.al., Functional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11733510
• Susanne. Granholm, et.al., Expression of the calcitonin receptor, calcitonin receptor-like receptor, and receptor activity modifying proteins during osteoclast differentiation., Journal of cellular biochemistry, 2008, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/18384073
• Sophocles. Chrissobolis, et.al., Receptor activity-modifying protein-1 augments cerebrovascular responses to calcitonin gene-related peptide and inhibits angiotensin II-induced vascular dysfunction., Stroke, 2010, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/20814003
• Blanca. Marquez de Prado, et.al., Genetic enhancement of calcitonin gene-related Peptide-induced central sensitization to mechanical stimuli in mice., The journal of pain : official journal of the American Pain Society, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19628434
• Y. Ono, et.al., Decreased gene expression of adrenomedullin receptor in mouse lungs during sepsis., Biochemical and biophysical research communications, 2000, 271
  http://rdf.ncbi.nlm.nih.gov/pubmed/10777702
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Kazutake. Tsujikawa, et.al., Hypertension and dysregulated proinflammatory cytokine production in receptor activity-modifying protein 1-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17923674
• K. Husmann, et.al., Mouse receptor-activity-modifying proteins 1, -2 and -3: amino acid sequence, expression and function., Molecular and cellular endocrinology, 2000, 162
  http://rdf.ncbi.nlm.nih.gov/pubmed/10854696

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• calcium ion transport
  http://purl.obolibrary.org/obo/GO_0006816
• protein transporter activity
  http://purl.obolibrary.org/obo/GO_0008565
• receptor complex
  http://purl.obolibrary.org/obo/GO_0043235
• angiogenesis
  http://purl.obolibrary.org/obo/GO_0001525
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• protein localization to plasma membrane
  http://purl.obolibrary.org/obo/GO_0072659
• regulation of G-protein coupled receptor protein signaling pathway
  http://purl.obolibrary.org/obo/GO_0008277
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• protein transport
  http://purl.obolibrary.org/obo/GO_0015031
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• positive regulation of protein glycosylation
  http://purl.obolibrary.org/obo/GO_0060050
• receptor internalization
  http://purl.obolibrary.org/obo/GO_0031623
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• coreceptor activity
  http://purl.obolibrary.org/obo/GO_0015026
• intracellular protein transport
  http://purl.obolibrary.org/obo/GO_0006886
• positive regulation of cAMP biosynthetic process
  http://purl.obolibrary.org/obo/GO_0030819
• calcitonin receptor binding
  http://purl.obolibrary.org/obo/GO_0031716
• calcitonin receptor activity
  http://purl.obolibrary.org/obo/GO_0004948
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• intracellular part
  http://purl.obolibrary.org/obo/GO_0044424

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04270

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Vascular smooth muscle contraction