CD02726

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02726

CD02726

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mfge8

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• milk fat globule-EGF factor 8 protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• milk fat globule-EGF factor 8 protein
• sperm surface protein SP47
• milk fat globule glycoprotein
• MP47

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Mfgm
• lactadherin
• MFG-E8
• EGF/factor VIII
• AA408458
• SED1
• P47
• AI325141

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17304

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• milk fat globule-EGF factor 8 protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:102768

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001045489
• https://www.ncbi.nlm.nih.gov/nuccore/NM_008594

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000030605

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.1451

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602281

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Adam S. Raymond, et.al., Loss of SED1/MFG-E8 results in altered luminal physiology in the epididymis., Molecular reproduction and development, 2010, 77
  http://rdf.ncbi.nlm.nih.gov/pubmed/20422713
• N. Aoki, et.al., Molecular cloning of glycoprotein antigens MGP57/53 recognized by monoclonal antibodies raised against bovine milk fat globule membrane., Biochimica et biophysica acta, 1995, 1245
  http://rdf.ncbi.nlm.nih.gov/pubmed/8541316
• Chuanwei. Yang, et.al., The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers., Cancer research, 2011, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/21127199
• Jan. Kranich, et.al., Engulfment of cerebral apoptotic bodies controls the course of prion disease in a mouse strain-dependent manner., The Journal of experimental medicine, 2010, 207
  http://rdf.ncbi.nlm.nih.gov/pubmed/20837697
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• K. Ogura, et.al., Cloning and expression of cDNA for O-acetylation of GD3 ganglioside., Biochemical and biophysical research communications, 1996, 225
  http://rdf.ncbi.nlm.nih.gov/pubmed/8780713
• C. Collins, et.al., Mapping of a newly discovered human gene homologous to the apoptosis associated-murine mammary protein, MFG-E8, to chromosome 15q25., Genomics, 1997, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/9027496
• N. Aoki, et.al., Stage specific expression of milk fat globule membrane glycoproteins in mouse mammary gland: comparison of MFG-E8, butyrophilin, and CD36 with a major milk protein, beta-casein., Biochimica et biophysica acta, 1997, 1334
  http://rdf.ncbi.nlm.nih.gov/pubmed/9101712
• G. Sugano, et.al., Milk fat globule--epidermal growth factor--factor VIII (MFGE8)/lactadherin promotes bladder tumor development., Oncogene, 2011, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20956946
• J D. Stubbs, et.al., cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences., Proceedings of the National Academy of Sciences of the United States of America, 1990, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/2122462

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of apoptotic cell clearance
  http://purl.obolibrary.org/obo/GO_2000427
• phagocytosis, engulfment
  http://purl.obolibrary.org/obo/GO_0006911
• phosphatidylethanolamine binding
  http://purl.obolibrary.org/obo/GO_0008429
• positive regulation of phagocytosis
  http://purl.obolibrary.org/obo/GO_0050766
• integrin binding
  http://purl.obolibrary.org/obo/GO_0005178
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• phosphatidylserine binding
  http://purl.obolibrary.org/obo/GO_0001786
• angiogenesis
  http://purl.obolibrary.org/obo/GO_0001525
• extrinsic component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0019897
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• single fertilization
  http://purl.obolibrary.org/obo/GO_0007338
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• phagocytosis, recognition
  http://purl.obolibrary.org/obo/GO_0006910
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• membrane
  http://purl.obolibrary.org/obo/GO_0016020

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName