CD02877

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02877

CD02877

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Gadd45b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• growth arrest and DNA-damage-inducible 45 beta

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• negative growth regulatory protein MyD118
• growth arrest and DNA-damage-inducible 45 beta
• growth arrest and DNA damage-inducible protein GADD45 beta
• myeloid differentiation primary response gene 118
• growth arrest and DNA-damage-inducible protein GADD45 beta
• myeloid differentiation primary response protein MyD118

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI323528
• Myd118

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/17873

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• growth arrest and DNA-damage-inducible 45 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:107776

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008655

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000015312

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.1360

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604948

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Hee Jun. Cho, et.al., Gadd45b mediates Fas-induced apoptosis by enhancing the interaction between p38 and retinoblastoma tumor suppressor., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20558744
• A G. Balliet, et.al., Comparative analysis of the genetic structure and chromosomal location of the murine MyD118 (Gadd45beta) gene., DNA and cell biology, 2001, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/11403721
• Rongguan. Jin, et.al., Regulation of the gadd45beta promoter by NF-kappaB., DNA and cell biology, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12162804
• Yuki. Okada, et.al., A role for the elongator complex in zygotic paternal genome demethylation., Nature, 2010, 463
  http://rdf.ncbi.nlm.nih.gov/pubmed/20054296
• K P. Brady, et.al., Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis., Genome research, 1997, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9371744
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Arshad. Amanullah, et.al., Cell signalling: cell survival and a Gadd45-factor deficiency., Nature, 2003, 424
  http://rdf.ncbi.nlm.nih.gov/pubmed/12917673
• Yukio. Yamamoto, et.al., Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20404936
• Kaneyuki. Tsuchimochi, et.al., GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytes., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20048163
• Mariappan. Vairapandi, et.al., GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress., Journal of cellular physiology, 2002, 192
  http://rdf.ncbi.nlm.nih.gov/pubmed/12124778
• A. Abdollahi, et.al., Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines., Oncogene, 1991, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/1899477

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• negative regulation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0006469
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• activation of MAPKK activity
  http://purl.obolibrary.org/obo/GO_0000186
• regulation of cell cycle
  http://purl.obolibrary.org/obo/GO_0051726
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04115
• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map04110

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• p53 signaling pathway
• Cell cycle
• MAPK signaling pathway