CD02894

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02894

CD02894

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Dab2ip

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• disabled homolog 2 (Drosophila) interacting protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• ASK1-interacting protein 1
• disabled homolog 2 (Drosophila) interacting protein
• disabled 2 interacting protein long form
• DAB2-interacting protein
• disabled homolog 2-interacting protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AIP1
• Aip1
• AI480459
• 2310011D08Rik
• mKIAA1743

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/69601

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• disabled 2 interacting protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916851

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001001602
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001114124
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001114125

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000026883

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.29629

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=609205

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Daxing. Xie, et.al., Role of DAB2IP in modulating epithelial-to-mesenchymal transition and prostate cancer metastasis., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080667
• Haifeng. Zhang, et.al., AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activation., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15310755
• Richard P. Munton, et.al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations., Molecular & cellular proteomics : MCP, 2007, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/17114649
• Junxia. Min, et.al., An oncogene-tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-kappaB., Nature medicine, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20154697
• Motoi. Nishimura, et.al., Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray., DNA research : an international journal for rapid publication of reports on genes and genomes, 2004, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/15747579
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Anne R M. von Bergh, et.al., Identification of a novel RAS GTPase-activating protein (RASGAP) gene at 9q34 as an MLL fusion partner in a patient with de novo acute myeloid leukemia., Genes, chromosomes & cancer, 2004, 39
  http://rdf.ncbi.nlm.nih.gov/pubmed/14978793
• Hong. Chen, et.al., Cloning of mouse Dab2ip gene, a novel member of the RasGTPase-activating protein family and characterization of its regulatory region in prostate., DNA and cell biology, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16629596
• Ramin. Homayouni, et.al., Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain., Brain research. Molecular brain research, 2003, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/12877983
• Chien-Ling. Huang, et.al., Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells., Journal of cellular physiology, 2010, 225
  http://rdf.ncbi.nlm.nih.gov/pubmed/20648627
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Ting. Wan, et.al., AIP1 functions as Arf6-GAP to negatively regulate TLR4 signaling., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/19948740

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• negative regulation of protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0071901
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• negative regulation of MAP kinase activity
  http://purl.obolibrary.org/obo/GO_0043407
• protein phosphatase 2A binding
  http://purl.obolibrary.org/obo/GO_0051721
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• positive regulation of JUN kinase activity
  http://purl.obolibrary.org/obo/GO_0043507
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• protein N-terminus binding
  http://purl.obolibrary.org/obo/GO_0047485
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• intrinsic component of the cytoplasmic side of the plasma membrane
  http://purl.obolibrary.org/obo/GO_0031235
• signaling adaptor activity
  http://purl.obolibrary.org/obo/GO_0035591
• negative regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0090090
• positive regulation of protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0071902
• death receptor binding
  http://purl.obolibrary.org/obo/GO_0005123
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• negative regulation of I-kappaB kinase/NF-kappaB signaling
  http://purl.obolibrary.org/obo/GO_0043124
• mitogen-activated protein kinase kinase kinase binding
  http://purl.obolibrary.org/obo/GO_0031435
• intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
  http://purl.obolibrary.org/obo/GO_0070059
• GTPase activator activity
  http://purl.obolibrary.org/obo/GO_0005096
• activation of JUN kinase activity
  http://purl.obolibrary.org/obo/GO_0007257
• cellular response to epidermal growth factor stimulus
  http://purl.obolibrary.org/obo/GO_0071364
• positive regulation of signal transduction
  http://purl.obolibrary.org/obo/GO_0009967
• negative regulation of NF-kappaB transcription factor activity
  http://purl.obolibrary.org/obo/GO_0032088
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• negative regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0034260
• negative regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048147
• negative regulation of Ras protein signal transduction
  http://purl.obolibrary.org/obo/GO_0046580
• 14-3-3 protein binding
  http://purl.obolibrary.org/obo/GO_0071889
• negative regulation of cell growth
  http://purl.obolibrary.org/obo/GO_0030308
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• negative regulation of epithelial to mesenchymal transition
  http://purl.obolibrary.org/obo/GO_0010719
• positive regulation of GTPase activity
  http://purl.obolibrary.org/obo/GO_0043547
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• cellular response to tumor necrosis factor
  http://purl.obolibrary.org/obo/GO_0071356
• regulation of small GTPase mediated signal transduction
  http://purl.obolibrary.org/obo/GO_0051056
• negative regulation of epidermal growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0042059
• negative regulation of epithelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0050680

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName