CD02899

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02899

CD02899

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Atp1a1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ATPase, Na+/K+ transporting, alpha 1 polypeptide

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• ATPase, Na+/K+ transporting, alpha 1 polypeptide
• sodium/potassium-transporting ATPase subunit alpha-1
• sodium pump subunit alpha-1
• Na(+)/K(+) ATPase alpha-1 subunit

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Atpa-1
• BC010319

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/11928

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ATPase, Na+/K+ transporting, alpha 1 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88105

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_144900

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000033161

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.280103

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=182310

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• A L. Boyle, et.al., Differential distribution of long and short interspersed element sequences in the mouse genome: chromosome karyotyping by fluorescence in situ hybridization., Proceedings of the National Academy of Sciences of the United States of America, 1990, 87
  http://rdf.ncbi.nlm.nih.gov/pubmed/2170987
• Hyoung-Mi. Kim, et.al., Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/21103348
• R J. Oakey, et.al., Chromosomal mapping of the high affinity Fc gamma receptor gene., Immunogenetics, 1992, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/1347284
• S F. Kingsmore, et.al., Long-range restriction site mapping of a syntenic segment conserved between human chromosome 1 and mouse chromosome 3., Genomics, 1990, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/1970802
• N A. Dower, et.al., Organization and chromosomal locations of Rap1a/Krev sequences in the mouse., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/1617222
• M. Nomoto, et.al., Analysis of cis-acting regions upstream of the rat Na+/K(+)-ATPase alpha 1 subunit gene by in vivo footprinting., Biochimica et biophysica acta, 1995, 1264
  http://rdf.ncbi.nlm.nih.gov/pubmed/7578254
• Satomi. Kita, et.al., [Mechanisms for linking high salt intake to vascular tone: role of Na(+) pump and Na(+)/Ca²(+) exchanger coupling]., Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/21048395
• Laura L. Yates, et.al., The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation., Human molecular genetics, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20843830
• M. Kobayashi, et.al., Synergism of the ATF/CRE site and GC box in the housekeeping Na,K-ATPase alpha1 subunit gene is essential for constitutive expression., Biochemical and biophysical research communications, 1997, 241
  http://rdf.ncbi.nlm.nih.gov/pubmed/9405252
• M. Yasue, et.al., Chromosomal assignments of 17 structural genes and 11 related DNA fragments in rats (Rattus norvegicus) by Southern blot analysis of rat x mouse somatic cell hybrid clones., Genomics, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1572638
• Arshani N. Wansapura, et.al., Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy., American journal of physiology. Heart and circulatory physiology, 2011, 300
  http://rdf.ncbi.nlm.nih.gov/pubmed/20952666
• Nobuyuki. Shiina, et.al., RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20861386

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• potassium ion transport
  http://purl.obolibrary.org/obo/GO_0006813
• sarcolemma
  http://purl.obolibrary.org/obo/GO_0042383
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• monovalent inorganic cation transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015077
• ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
  http://purl.obolibrary.org/obo/GO_0015662
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• ATPase activity, coupled to transmembrane movement of substances
  http://purl.obolibrary.org/obo/GO_0042626
• endosome
  http://purl.obolibrary.org/obo/GO_0005768
• sodium ion binding
  http://purl.obolibrary.org/obo/GO_0031402
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• potassium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0071805
• response to drug
  http://purl.obolibrary.org/obo/GO_0042493
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• regulation of blood pressure
  http://purl.obolibrary.org/obo/GO_0008217
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• monovalent inorganic cation transport
  http://purl.obolibrary.org/obo/GO_0015672
• protein domain specific binding
  http://purl.obolibrary.org/obo/GO_0019904
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• potassium ion import
  http://purl.obolibrary.org/obo/GO_0010107
• ADP binding
  http://purl.obolibrary.org/obo/GO_0043531
• sodium ion transport
  http://purl.obolibrary.org/obo/GO_0006814
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• phosphatidylinositol 3-kinase binding
  http://purl.obolibrary.org/obo/GO_0043548
• phosphatase activity
  http://purl.obolibrary.org/obo/GO_0016791
• sodium:potassium-exchanging ATPase activity
  http://purl.obolibrary.org/obo/GO_0005391
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• cation transport
  http://purl.obolibrary.org/obo/GO_0006812
• negative regulation of glucocorticoid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0031947
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• negative regulation of heart contraction
  http://purl.obolibrary.org/obo/GO_0045822
• regulation of the force of heart contraction
  http://purl.obolibrary.org/obo/GO_0002026
• potassium ion binding
  http://purl.obolibrary.org/obo/GO_0030955
• positive regulation of striated muscle contraction
  http://purl.obolibrary.org/obo/GO_0045989
• sodium ion export from cell
  http://purl.obolibrary.org/obo/GO_0036376
• sodium:potassium-exchanging ATPase complex
  http://purl.obolibrary.org/obo/GO_0005890
• basolateral plasma membrane
  http://purl.obolibrary.org/obo/GO_0016323
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• caveola
  http://purl.obolibrary.org/obo/GO_0005901
• regulation of sodium ion transport
  http://purl.obolibrary.org/obo/GO_0002028
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• ATP biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006754
• positive regulation of heart contraction
  http://purl.obolibrary.org/obo/GO_0045823
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04972
• http://www.genome.jp/dbget-bin/www_bget?map04260
• http://www.genome.jp/dbget-bin/www_bget?map04974
• http://www.genome.jp/dbget-bin/www_bget?map04970
• http://www.genome.jp/dbget-bin/www_bget?map04961
• http://www.genome.jp/dbget-bin/www_bget?map04973
• http://www.genome.jp/dbget-bin/www_bget?map04978
• http://www.genome.jp/dbget-bin/www_bget?map04971
• http://www.genome.jp/dbget-bin/www_bget?map04964
• http://www.genome.jp/dbget-bin/www_bget?map04976
• http://www.genome.jp/dbget-bin/www_bget?map04960

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Pancreatic secretion
• Carbohydrate digestion and absorption
• Protein digestion and absorption
• Proximal tubule bicarbonate reclamation
• Mineral absorption
• Gastric acid secretion
• Endocrine and other factor-regulated calcium reabsorption
• Cardiac muscle contraction
• Salivary secretion
• Aldosterone-regulated sodium reabsorption
• Bile secretion