CD02917

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02917

CD02917

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Xbp1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• X-box binding protein 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• X-box binding protein 1
• X-box-binding protein 1
• tax-responsive element-binding protein 5 homolog

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• TREB5
• D11Ertd39e
• TREB-5
• XBP-1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/22433

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• X-box binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:98970

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_013842

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020484

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.469937

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=194355

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• T. Masaki, et.al., Isolation and characterization of the gene encoding mouse tax-responsive element-binding protein (TREB) 5., DNA research : an international journal for rapid publication of reports on genes and genomes, 2000, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/10907849
• A M. Reimold, et.al., An essential role in liver development for transcription factor XBP-1., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10652269
• D. ten Berge, et.al., Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm., Developmental biology, 1998, 199
  http://rdf.ncbi.nlm.nih.gov/pubmed/9676189
• Feng-Ming. Wang, et.al., Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation., The Biochemical journal, 2011, 433
  http://rdf.ncbi.nlm.nih.gov/pubmed/20955178
• Won Jae. Huh, et.al., XBP1 controls maturation of gastric zymogenic cells by induction of MIST1 and expansion of the rough endoplasmic reticulum., Gastroenterology, 2010, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/20816838
• Jingming. Li, et.al., Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21138840
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Atsushi. Takata, et.al., Behavioral and gene expression analyses in heterozygous XBP1 knockout mice: Possible contribution of chromosome 11qA1 locus to prepulse inhibition., Neuroscience research, 2010, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/20692302
• I M. Clauss, et.al., In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis., Developmental dynamics : an official publication of the American Association of Anatomists, 1993, 197
  http://rdf.ncbi.nlm.nih.gov/pubmed/7693055
• T. Masaki, et.al., Targeted disruption of CRE-binding factor TREB5 gene leads to cellular necrosis in cardiac myocytes at the embryonic stage., Biochemical and biophysical research communications, 1999, 261
  http://rdf.ncbi.nlm.nih.gov/pubmed/10425189
• Marcella. Calfon, et.al., IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA., Nature, 2002, 415
  http://rdf.ncbi.nlm.nih.gov/pubmed/11780124

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• epithelial cell maturation
  http://purl.obolibrary.org/obo/GO_0002070
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• epithelial cell maturation involved in salivary gland development
  http://purl.obolibrary.org/obo/GO_0060691
• endoplasmic reticulum unfolded protein response
  http://purl.obolibrary.org/obo/GO_0030968
• serotonin secretion, neurotransmission
  http://purl.obolibrary.org/obo/GO_0060096
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006366
• exocrine pancreas development
  http://purl.obolibrary.org/obo/GO_0031017
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• protein dimerization activity
  http://purl.obolibrary.org/obo/GO_0046983
• response to electrical stimulus
  http://purl.obolibrary.org/obo/GO_0051602
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• response to drug
  http://purl.obolibrary.org/obo/GO_0042493

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04141

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• HTLV-I infection
• Protein processing in endoplasmic reticulum