CD02924

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02924

CD02924

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cplx1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• complexin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• complexin I
• CPX I
• synaphin-2
• complexin 1
• complexin-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 921-S

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12889

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• complexin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:104727

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007756

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000033615

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.5195

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605032

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Mingshan. Xue, et.al., Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis., Neuron, 2009, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/19914185
• H. Tokumaru, et.al., SNARE complex oligomerization by synaphin/complexin is essential for synaptic vesicle exocytosis., Cell, 2001, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/11239399
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Mingshan. Xue, et.al., Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity., Nature structural & molecular biology, 2010, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/20400951
• Sandrine. Thuret, et.al., Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta., Molecular and cellular neurosciences, 2004, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15033168
• Whitney. Freeman, et.al., Differential messenger RNA expression of complexins in mouse brain., Brain research bulletin, 2004, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/15121237
• Karla E. Marz, et.al., Sealed with a twist: complexin and the synaptic SNARE complex., Trends in neurosciences, 2002, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/12127744
• H T. McMahon, et.al., Complexins: cytosolic proteins that regulate SNAP receptor function., Cell, 1995, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/7553862
• Xiaofei. Yang, et.al., Complexin clamps asynchronous release by blocking a secondary Ca(2+) sensor via its accessory α helix., Neuron, 2010, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/21145004
• S. Takahashi, et.al., Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses., FEBS letters, 1995, 368
  http://rdf.ncbi.nlm.nih.gov/pubmed/7635198
• K. Reim, et.al., Complexins regulate a late step in Ca2+-dependent neurotransmitter release., Cell, 2001, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/11163241
• João D. Pereira, et.al., Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20798045

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• SNARE complex
  http://purl.obolibrary.org/obo/GO_0031201
• neurotransmitter transport
  http://purl.obolibrary.org/obo/GO_0006836
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• SNARE binding
  http://purl.obolibrary.org/obo/GO_0000149
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• neurotransmitter transporter activity
  http://purl.obolibrary.org/obo/GO_0005326
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• synaptic vesicle exocytosis
  http://purl.obolibrary.org/obo/GO_0016079
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• syntaxin-1 binding
  http://purl.obolibrary.org/obo/GO_0017075
• exocytosis
  http://purl.obolibrary.org/obo/GO_0006887
• insulin secretion
  http://purl.obolibrary.org/obo/GO_0030073
• syntaxin binding
  http://purl.obolibrary.org/obo/GO_0019905
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425
• synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
  http://purl.obolibrary.org/obo/GO_0070032
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04721

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Synaptic vesicle cycle