CD03028

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03028

CD03028

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pip5k1b

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• phosphatidylinositol-4-phosphate 5-kinase, type 1 beta

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• phosphatidylinositol-4-phosphate 5-kinase type I alpha
• PIP5K1-beta
• PIP5KIbeta
• PIP5KIalpha
• ptdIns(4)P-5-kinase 1 beta
• PI4P5K-I[b]
• phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
• phosphatidylinositol-4-phosphate 5-kinase type-1 beta
• phosphatidylinositol-4-phosphate 5-kinase type I beta

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI844522
• Pipk5b
• STM7
• Pip5k1a
• Pipk5a
• PI4P5K-I[a]

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18719

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:107930

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008846

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024867

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.217214

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602745

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• R A. Anderson, et.al., Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10187762
• K F. Tolias, et.al., Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly., Current biology : CB, 2000, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/10679324
• H. Ishihara, et.al., Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9535851
• H. Ishihara, et.al., Cloning of cDNAs encoding two isoforms of 68-kDa type I phosphatidylinositol-4-phosphate 5-kinase., The Journal of biological chemistry, 1996, 271
  http://rdf.ncbi.nlm.nih.gov/pubmed/8798574
• J N. Davis, et.al., Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase., Molecular and cellular biology, 1997, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/9372970
• Yanfeng. Wang, et.al., Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes., The Journal of clinical investigation, 2008, 118
  http://rdf.ncbi.nlm.nih.gov/pubmed/18188447
• Laura A. Volpicelli-Daley, et.al., Phosphatidylinositol-4-phosphate 5-kinases and phosphatidylinositol 4,5-bisphosphate synthesis in the brain., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20622009
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Lavanya. Vasudevan, et.al., The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells., Journal of cell science, 2009, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/19549683
• Yanfeng. Wang, et.al., Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/18772378

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• phosphatidylinositol phosphate kinase activity
  http://purl.obolibrary.org/obo/GO_0016307
• 1-phosphatidylinositol-4-phosphate 5-kinase activity
  http://purl.obolibrary.org/obo/GO_0016308
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• phosphatidylinositol phosphorylation
  http://purl.obolibrary.org/obo/GO_0046854
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• phosphatidylinositol metabolic process
  http://purl.obolibrary.org/obo/GO_0046488
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• uropod
  http://purl.obolibrary.org/obo/GO_0001931

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144
• http://www.genome.jp/dbget-bin/www_bget?map01100
• http://www.genome.jp/dbget-bin/www_bget?map00562
• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map04666
• http://www.genome.jp/dbget-bin/www_bget?map04070

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Fc gamma R-mediated phagocytosis
• Phosphatidylinositol signaling system
• Regulation of actin cytoskeleton
• Metabolic pathways
• Inositol phosphate metabolism
• Endocytosis