CD03128

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03128

CD03128

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Casp9

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• caspase 9

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• caspase 9
• caspase-9

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ICE-LAP6
• AI115399
• Caspase-9
• AW493809
• Mch6

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12371

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• caspase 9
  http://metadb.riken.jp/db/mgi_rdf/MGI:1277950

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_015733

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000028914

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.88829
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.468800

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602234

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Flavie. Strappazzon, et.al., Alix is involved in caspase 9 activation during calcium-induced apoptosis., Biochemical and biophysical research communications, 2010, 397
  http://rdf.ncbi.nlm.nih.gov/pubmed/20471954
• Shizue. Ohsawa, et.al., Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20624980
• K. Sakamaki, et.al., Molecular cloning and characterization of mouse caspase-8., European journal of biochemistry, 1998, 253
  http://rdf.ncbi.nlm.nih.gov/pubmed/9654089
• S. Kumar, et.al., Prodomains--adaptors--oligomerization: the pursuit of caspase activation in apoptosis., Trends in biochemical sciences, 1999, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/10087912
• Rachel Wilson. Goehe, et.al., hnRNP L regulates the tumorigenic capacity of lung cancer xenografts in mice via caspase-9 pre-mRNA processing., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20972334
• Noriaki. Matsuki, et.al., Activation of caspases and apoptosis in response to low-voltage electric pulses., Oncology reports, 2010, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/20372860
• V. Viswanath, et.al., Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11739563
• R. Hakem, et.al., Differential requirement for caspase 9 in apoptotic pathways in vivo., Cell, 1998, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9708736
• K. Kuida, et.al., Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9., Cell, 1998, 94
  http://rdf.ncbi.nlm.nih.gov/pubmed/9708735
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Vanessa S. Marsden, et.al., Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome., Nature, 2002, 419
  http://rdf.ncbi.nlm.nih.gov/pubmed/12374983
• P. Li, et.al., Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade., Cell, 1997, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/9390557
• M. Los, et.al., The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice., Immunity, 1999, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/10403638

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• cellular response to dexamethasone stimulus
  http://purl.obolibrary.org/obo/GO_0071549
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• cysteine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008234
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• activation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0006919
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• peptide binding
  http://purl.obolibrary.org/obo/GO_0042277
• activation of cysteine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0097202
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• response to organic cyclic compound
  http://purl.obolibrary.org/obo/GO_0014070
• positive regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043525
• response to UV
  http://purl.obolibrary.org/obo/GO_0009411
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043280
• apoptosome
  http://purl.obolibrary.org/obo/GO_0043293
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05223
• http://www.genome.jp/dbget-bin/www_bget?map04370
• http://www.genome.jp/dbget-bin/www_bget?map04210
• http://www.genome.jp/dbget-bin/www_bget?map05134
• http://www.genome.jp/dbget-bin/www_bget?map05215
• http://www.genome.jp/dbget-bin/www_bget?map05164
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05010
• http://www.genome.jp/dbget-bin/www_bget?map05012
• http://www.genome.jp/dbget-bin/www_bget?map05014
• http://www.genome.jp/dbget-bin/www_bget?map05213
• http://www.genome.jp/dbget-bin/www_bget?map05145
• http://www.genome.jp/dbget-bin/www_bget?map05222
• http://www.genome.jp/dbget-bin/www_bget?map05210
• http://www.genome.jp/dbget-bin/www_bget?map05212
• http://www.genome.jp/dbget-bin/www_bget?map05016
• http://www.genome.jp/dbget-bin/www_bget?map04115
• http://www.genome.jp/dbget-bin/www_bget?map05152
• http://www.genome.jp/dbget-bin/www_bget?map05416

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Tuberculosis
• VEGF signaling pathway
• Endometrial cancer
• Prostate cancer
• Small cell lung cancer
• Legionellosis
• p53 signaling pathway
• Non-small cell lung cancer
• Alzheimer's disease
• Parkinson's disease
• Influenza A
• Pancreatic cancer
• Viral myocarditis
• Pathways in cancer
• Apoptosis
• Toxoplasmosis
• Colorectal cancer
• Huntington's disease
• Amyotrophic lateral sclerosis (ALS)