CD03138

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03138

CD03138

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Dpysl2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• dihydropyrimidinase-like 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• DRP-2
• collapsin response mediator protein 2
• dihydropyrimidinase-related protein 2
• ULIP-2
• dihydropyrimidinase-like 2
• unc-33-like phosphoprotein 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• DRP2
• unc-33
• Musunc33
• unc33
• Ulip2
• AI851130
• TOAD-64
• Crmp2

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12934

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• dihydropyrimidinase-like 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1349763

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009955

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022048

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.352648
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.475100

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602463

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Kenneth. Hensley, et.al., Proteomic identification of binding partners for the brain metabolite lanthionine ketimine (LK) and documentation of LK effects on microglia and motoneuron cell cultures., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20181595
• A K. Dixon, et.al., Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse., Journal of molecular biology, 1997, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/9245586
• T. Kamata, et.al., Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance., Brain research. Molecular brain research, 1998, 54
  http://rdf.ncbi.nlm.nih.gov/pubmed/9555025
• T. Byk, et.al., The Ulip family phosphoproteins--common and specific properties., European journal of biochemistry, 1998, 254
  http://rdf.ncbi.nlm.nih.gov/pubmed/9652388
• Yutaka. Uchida, et.al., Semaphorin3A signaling mediated by Fyn-dependent tyrosine phosphorylation of collapsin response mediator protein 2 at tyrosine 32., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19652227
• T. Ito, et.al., Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung., Mechanisms of development, 2000, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/11025205
• N. Hamajima, et.al., A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution., Gene, 1996, 180
  http://rdf.ncbi.nlm.nih.gov/pubmed/8973361
• Joel M. Brittain, et.al., An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19755421
• Sébastien. Brot, et.al., CRMP5 interacts with tubulin to inhibit neurite outgrowth, thereby modulating the function of CRMP2., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20702696
• N. Inagaki, et.al., CRMP-2 induces axons in cultured hippocampal neurons., Nature neuroscience, 2001, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/11477421
• H. Inagaki, et.al., Differential expression of dihydropyrimidinase-related protein genes in developing and adult enteric nervous system., Histochemistry and cell biology, 2000, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/10664068
• Teng. Fei, et.al., Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination., Genome research, 2010, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19926752
• Takashi. Nishimura, et.al., CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth., Nature cell biology, 2003, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/12942088

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• terminal bouton
  http://purl.obolibrary.org/obo/GO_0043195
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• neuronal cell body
  http://purl.obolibrary.org/obo/GO_0043025
• hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
  http://purl.obolibrary.org/obo/GO_0016810
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• synaptic vesicle transport
  http://purl.obolibrary.org/obo/GO_0048489
• growth cone
  http://purl.obolibrary.org/obo/GO_0030426
• positive regulation of glutamate secretion
  http://purl.obolibrary.org/obo/GO_0014049
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• pyrimidine nucleobase catabolic process
  http://purl.obolibrary.org/obo/GO_0006208
• hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
  http://purl.obolibrary.org/obo/GO_0016812
• regulation of neuron differentiation
  http://purl.obolibrary.org/obo/GO_0045664
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• axon
  http://purl.obolibrary.org/obo/GO_0030424
• soluble fraction
  http://purl.obolibrary.org/obo/GO_0005625
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• dendrite
  http://purl.obolibrary.org/obo/GO_0030425

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04360

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Axon guidance