CD03158

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03158

CD03158

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Col4a3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• collagen, type IV, alpha 3

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• collagen, type IV, alpha 3
• collagen type IV alpha3 chain
• procollagen, type IV, alpha 3
• collagen alpha-3(IV) chain

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• tumstatin
• alpha3(IV)
• [a]3(IV)

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12828

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• collagen, type IV, alpha 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:104688

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007734

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000079465

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.389135

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=120070

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Oliver. Gross, et.al., Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease., Matrix biology : journal of the International Society for Matrix Biology, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20307660
• D. Cosgrove, et.al., Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome., Genes & development, 1996, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/8956999
• Valerie. LeBleu, et.al., Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20847057
• Mari. Tanaka, et.al., Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20197625
• J E. Wu, et.al., Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development., Developmental dynamics : an official publication of the American Association of Anatomists, 1994, 199
  http://rdf.ncbi.nlm.nih.gov/pubmed/7521231
• Dale R. Abrahamson, et.al., Cellular origins of type IV collagen networks in developing glomeruli., Journal of the American Society of Nephrology : JASN, 2009, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/19423686
• Y. Saga, et.al., Mice develop normally without tenascin., Genes & development, 1992, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/1383086
• J H. Miner, et.al., Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches., The Journal of cell biology, 1994, 127
  http://rdf.ncbi.nlm.nih.gov/pubmed/7962065
• Jameel. Dennis, et.al., Collagen XIII induced in vascular endothelium mediates alpha1beta1 integrin-dependent transmigration of monocytes in renal fibrosis., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20864678
• Laurence. Heidet, et.al., A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice., The American journal of pathology, 2003, 163
  http://rdf.ncbi.nlm.nih.gov/pubmed/14507670
• G C. Enders, et.al., Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis., Biology of reproduction, 1995, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/8562707
• S. Tajbakhsh, et.al., Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice., Nature, 1996, 384
  http://rdf.ncbi.nlm.nih.gov/pubmed/8918877

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• activation of cysteine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0097202
• extracellular matrix structural constituent
  http://purl.obolibrary.org/obo/GO_0005201
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• proteinaceous extracellular matrix
  http://purl.obolibrary.org/obo/GO_0005578
• basement membrane
  http://purl.obolibrary.org/obo/GO_0005604
• cell surface receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007166
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• negative regulation of angiogenesis
  http://purl.obolibrary.org/obo/GO_0016525
• collagen
  http://purl.obolibrary.org/obo/GO_0005202
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• glomerular basement membrane development
  http://purl.obolibrary.org/obo/GO_0032836
• activation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0006919
• positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043280
• binding
  http://purl.obolibrary.org/obo/GO_0005488
• cell proliferation
  http://purl.obolibrary.org/obo/GO_0008283
• integrin binding
  http://purl.obolibrary.org/obo/GO_0005178

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName