CD03162

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03162

CD03162

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Bdnf

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• brain derived neurotrophic factor

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• brain-derived neurotrophic factor
• brain derived neurotrophic factor
• anorexia BDNF

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12064

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• brain derived neurotrophic factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:88145

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007540
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001048139
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001048141
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001048142

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000048482

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.1442

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=113505

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• O. Guillin, et.al., BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization., Nature, 2001, 411
  http://rdf.ncbi.nlm.nih.gov/pubmed/11333982
• Niki. Panagiotaki, et.al., Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/21062861
• A. Hohn, et.al., Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family., Nature, 1990, 344
  http://rdf.ncbi.nlm.nih.gov/pubmed/2314473
• P C. Maisonpierre, et.al., NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression., Neuron, 1990, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/1688327
• Baoji. Xu, et.al., Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor., Nature neuroscience, 2003, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/12796784
• D. Soppet, et.al., The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor., Cell, 1991, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/1645620
• Maryna. Baydyuk, et.al., TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21205893
• Luye. Qin, et.al., Genetic variant of BDNF (Val66Met) polymorphism attenuates stroke-induced angiogenic responses by enhancing anti-angiogenic mediator CD36 expression., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21228186
• S R. D'Mello, et.al., Differential regulation of the nerve growth factor and brain-derived neurotrophic factor genes in L929 mouse fibroblasts., Journal of neuroscience research, 1992, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/1336558
• M A. Bothwell, et.al., Dissociation equilibrium constant of beta nerve growth factor., The Journal of biological chemistry, 1977, 252
  http://rdf.ncbi.nlm.nih.gov/pubmed/925010
• Danielle E. Harlow, et.al., Epibranchial placode-derived neurons produce BDNF required for early sensory neuron development., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21246648
• T. Ozçelik, et.al., Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse., Genomics, 1991, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/1889807
• Tao. Huang, et.al., Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239
  http://rdf.ncbi.nlm.nih.gov/pubmed/21038447

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• mitochondrial electron transport, NADH to ubiquinone
  http://purl.obolibrary.org/obo/GO_0006120
• dendrite development
  http://purl.obolibrary.org/obo/GO_0016358
• regulation of metabolic process
  http://purl.obolibrary.org/obo/GO_0019222
• axon target recognition
  http://purl.obolibrary.org/obo/GO_0007412
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• regulation of short-term neuronal synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048172
• growth factor activity
  http://purl.obolibrary.org/obo/GO_0008083
• regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043523
• ureteric bud development
  http://purl.obolibrary.org/obo/GO_0001657
• inner ear development
  http://purl.obolibrary.org/obo/GO_0048839
• negative regulation of neuroblast proliferation
  http://purl.obolibrary.org/obo/GO_0007406
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• regulation of retinal cell programmed cell death
  http://purl.obolibrary.org/obo/GO_0046668
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• glutamate secretion
  http://purl.obolibrary.org/obo/GO_0014047
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• behavior
  http://purl.obolibrary.org/obo/GO_0007610
• regulation of long-term neuronal synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048169
• neurotrophin TRKB receptor binding
  http://purl.obolibrary.org/obo/GO_0005169
• positive regulation of long-term neuronal synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048170
• positive regulation of neuron differentiation
  http://purl.obolibrary.org/obo/GO_0045666
• response to drug
  http://purl.obolibrary.org/obo/GO_0042493
• negative regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043524
• neuron recognition
  http://purl.obolibrary.org/obo/GO_0008038
• synaptic vesicle
  http://purl.obolibrary.org/obo/GO_0008021
• regulation of compound eye retinal cell programmed cell death
  http://purl.obolibrary.org/obo/GO_0046669
• fear response
  http://purl.obolibrary.org/obo/GO_0042596
• mechanoreceptor differentiation
  http://purl.obolibrary.org/obo/GO_0042490
• learning or memory
  http://purl.obolibrary.org/obo/GO_0007611
• feeding behavior
  http://purl.obolibrary.org/obo/GO_0007631
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• regulation of synaptic plasticity
  http://purl.obolibrary.org/obo/GO_0048167
• negative regulation of striated muscle tissue development
  http://purl.obolibrary.org/obo/GO_0045843
• nerve development
  http://purl.obolibrary.org/obo/GO_0021675

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05016
• http://www.genome.jp/dbget-bin/www_bget?map04722
• http://www.genome.jp/dbget-bin/www_bget?map04010

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• MAPK signaling pathway
• Neurotrophin signaling pathway
• Huntington's disease