CD03194

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03194

CD03194

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Gphn

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• gephyrin

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• gephyrin

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C230040D23
• AI662856
• GPHRYN
• BC027112
• 5730552E08Rik
• geph
• GPH

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/268566

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• gephyrin
  http://metadb.riken.jp/db/mgi_rdf/MGI:109602

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_172952
• https://www.ncbi.nlm.nih.gov/nuccore/NM_145965

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000047454

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.453131
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.363753
• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.341742

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603930

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Patricia. Machado, et.al., Heat shock cognate protein 70 regulates gephyrin clustering., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21209184
• J. Meier, et.al., Fast and reversible trapping of surface glycine receptors by gephyrin., Nature neuroscience, 2001, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/11224541
• Shiva K. Tyagarajan, et.al., Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21173228
• M. Kneussel, et.al., The gamma-aminobutyric acid type A receptor (GABAAR)-associated protein GABARAP interacts with gephyrin but is not involved in receptor anchoring at the synapse., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/10900017
• G. Feng, et.al., Dual requirement for gephyrin in glycine receptor clustering and molybdoenzyme activity., Science (New York, N.Y.), 1998, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/9812897
• A S. Serpinskaya, et.al., Synapse formation by hippocampal neurons from agrin-deficient mice., Developmental biology, 1999, 205
  http://rdf.ncbi.nlm.nih.gov/pubmed/9882498
• Lucian. Medrihan, et.al., Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses., The Journal of physiology, 2009, 587
  http://rdf.ncbi.nlm.nih.gov/pubmed/19723784
• M. Kneussel, et.al., Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice., The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/10531433
• M. Ramming, et.al., Analysis of the promoter region of the murine gephyrin gene., FEBS letters, 1997, 405
  http://rdf.ncbi.nlm.nih.gov/pubmed/9089277
• Nobuyuki. Shiina, et.al., RNG105 deficiency impairs the dendritic localization of mRNAs for Na+/K+ ATPase subunit isoforms and leads to the degeneration of neuronal networks., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20861386

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• cytoskeletal protein binding
  http://purl.obolibrary.org/obo/GO_0008092
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• postsynaptic membrane
  http://purl.obolibrary.org/obo/GO_0045211
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• protein homooligomerization
  http://purl.obolibrary.org/obo/GO_0051260
• establishment of protein localization
  http://purl.obolibrary.org/obo/GO_0045184
• establishment of synaptic specificity at neuromuscular junction
  http://purl.obolibrary.org/obo/GO_0007529
• inhibitory synapse
  http://purl.obolibrary.org/obo/GO_0060077
• extrinsic component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0019897
• Mo-molybdopterin cofactor biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006777
• molybdopterin cofactor biosynthetic process
  http://purl.obolibrary.org/obo/GO_0032324

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04727

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• GABAergic synapse