CD03247

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03247

CD03247

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Nefh

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• neurofilament, heavy polypeptide

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• neurofilament heavy polypeptide
• neurofilament 200kDa
• 200 kDa neurofilament protein
• neurofilament, heavy polypeptide
• neurofilament triplet H protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• NEFH
• mKIAA0845
• Nfh
• NF-H
• NF200

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/380684

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• neurofilament, heavy polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:97309

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010904

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000020396

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.298283

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=162230

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Sophie. Grimal, et.al., Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells., Glia, 2010, 58
  http://rdf.ncbi.nlm.nih.gov/pubmed/20830809
• H. Shen, et.al., Distal to proximal development of peripheral nerves requires the expression of neurofilament heavy., Neuroscience, 2010, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/20633607
• Jie. Chen, et.al., Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21228161
• P S. Shneidman, et.al., Negative regulatory regions are present upstream in the three mouse neurofilament genes., Brain research. Molecular brain research, 1992, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1315909
• A. Petzold, et.al., Quantification of neurodegeneration by measurement of brain-specific proteins., Journal of neuroimmunology, 2003, 138
  http://rdf.ncbi.nlm.nih.gov/pubmed/12742652
• J F. Lees, et.al., The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it., The EMBO journal, 1988, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/3138108
• K. Kaupmann, et.al., Wobbler, a mutation affecting motoneuron survival and gonadal functions in the mouse, maps to proximal chromosome 11., Genomics, 1992, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1349581
• A. Petzold, et.al., A specific ELISA for measuring neurofilament heavy chain phosphoforms., Journal of immunological methods, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12957406
• Sharon. Haramati, et.al., miRNA malfunction causes spinal motor neuron disease., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20616011
• D S. Whitlon, et.al., NCAM in the organ of Corti of the developing mouse., Journal of neurocytology, 1990, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/2292721
• J P. Julien, et.al., Cloning and developmental expression of the murine neurofilament gene family., Brain research, 1986, 387
  http://rdf.ncbi.nlm.nih.gov/pubmed/3103856
• Roberta. Sottocornola, et.al., ASPP2 binds Par-3 and controls the polarity and proliferation of neural progenitors during CNS development., Developmental cell, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/20619750

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• intermediate filament
  http://purl.obolibrary.org/obo/GO_0005882
• neurofilament
  http://purl.obolibrary.org/obo/GO_0005883
• intermediate filament cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0045104
• neurofilament cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0060052
• intermediate filament bundle assembly
  http://purl.obolibrary.org/obo/GO_0045110
• nutrient reservoir activity
  http://purl.obolibrary.org/obo/GO_0045735
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• microtubule cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0000226

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05014

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Amyotrophic lateral sclerosis (ALS)