CD03266

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03266

CD03266

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ngfr

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• nerve growth factor receptor (TNFR superfamily, member 16)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• NGF receptor
• low affinity neurotrophin receptor p75NTR
• low-affinity nerve growth factor receptor
• nerve growth factor receptor (TNFR superfamily, member 16)
• tumor necrosis factor receptor superfamily member 16

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• LNGFR
• Tnfrsf16
• p75
• p75 neurotrophin receptor
• p75NGFR
• p75NTR

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18053

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• nerve growth factor receptor (TNFR superfamily, member 16)
  http://metadb.riken.jp/db/mgi_rdf/MGI:97323

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_033217

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000000120

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.283893

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=162010

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K F. Lee, et.al., Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system., Cell, 1992, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/1317267
• M V. Chao, Neurotrophin receptors: a window into neuronal differentiation., Neuron, 1992, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/1327010
• R J. Cornall, et.al., Mouse microsatellites from a flow-sorted 4:6 Robertsonian chromosome., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/1450512
• T. Serikawa, et.al., Rat gene mapping using PCR-analyzed microsatellites., Genetics, 1992, 131
  http://rdf.ncbi.nlm.nih.gov/pubmed/1628813
• A. Blanchart, et.al., Peripheral contributions to olfactory bulb cell populations (migrations towards the olfactory bulb)., Glia, 2011, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/21125652
• Zhishan. Li, et.al., Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148012
他4件を見る
• Paul. Gibson, et.al., Subtypes of medulloblastoma have distinct developmental origins., Nature, 2010, 468
  http://rdf.ncbi.nlm.nih.gov/pubmed/21150899
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Yan-Jiang. Wang, et.al., p75NTR regulates Abeta deposition by increasing Abeta production but inhibiting Abeta aggregation with its extracellular domain., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21307265
• A. Sutter, et.al., Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells., The Journal of biological chemistry, 1979, 254
  http://rdf.ncbi.nlm.nih.gov/pubmed/571871

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• beta-amyloid binding
  http://purl.obolibrary.org/obo/GO_0001540
• death receptor activity
  http://purl.obolibrary.org/obo/GO_0005035
• neurotrophin TRKA receptor binding
  http://purl.obolibrary.org/obo/GO_0005168
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• nuclear envelope
  http://purl.obolibrary.org/obo/GO_0005635
他46件を見る
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• rough endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005791
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• central nervous system development
  http://purl.obolibrary.org/obo/GO_0007417
• response to wounding
  http://purl.obolibrary.org/obo/GO_0009611
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010468
• positive regulation of cell death
  http://purl.obolibrary.org/obo/GO_0010942
• negative regulation of neuron projection development
  http://purl.obolibrary.org/obo/GO_0010977
• detection of temperature stimulus
  http://purl.obolibrary.org/obo/GO_0016048
• sensory perception of pain
  http://purl.obolibrary.org/obo/GO_0019233
• nerve development
  http://purl.obolibrary.org/obo/GO_0021675
• coated vesicle
  http://purl.obolibrary.org/obo/GO_0030135
• hair follicle morphogenesis
  http://purl.obolibrary.org/obo/GO_0031069
• positive regulation of myelination
  http://purl.obolibrary.org/obo/GO_0031643
• positive regulation of synaptic transmission, cholinergic
  http://purl.obolibrary.org/obo/GO_0032224
• dendrite membrane
  http://purl.obolibrary.org/obo/GO_0032590
• neuronal cell body membrane
  http://purl.obolibrary.org/obo/GO_0032809
• cellular response to oxidative stress
  http://purl.obolibrary.org/obo/GO_0034599
• positive regulation of Rho protein signal transduction
  http://purl.obolibrary.org/obo/GO_0035025
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• negative regulation of fibroblast growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0040037
• positive regulation of odontogenesis of dentin-containing tooth
  http://purl.obolibrary.org/obo/GO_0042488
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• neurotrophin binding
  http://purl.obolibrary.org/obo/GO_0043121
• perikaryon
  http://purl.obolibrary.org/obo/GO_0043204
• positive regulation of MAPK cascade
  http://purl.obolibrary.org/obo/GO_0043410
• negative regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043524
• positive regulation of neuron apoptotic process
  http://purl.obolibrary.org/obo/GO_0043525
• skin development
  http://purl.obolibrary.org/obo/GO_0043588
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• clathrin-coated endocytic vesicle
  http://purl.obolibrary.org/obo/GO_0045334
• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146
• nerve growth factor binding
  http://purl.obolibrary.org/obo/GO_0048406
• negative regulation of hair follicle development
  http://purl.obolibrary.org/obo/GO_0051799
• positive regulation of protein kinase B signaling
  http://purl.obolibrary.org/obo/GO_0051897
• negative regulation of mitochondrial depolarization
  http://purl.obolibrary.org/obo/GO_0051902
• positive regulation of synaptic transmission, glutamatergic
  http://purl.obolibrary.org/obo/GO_0051968
• negative regulation of cell death
  http://purl.obolibrary.org/obo/GO_0060548
• preprotein binding
  http://purl.obolibrary.org/obo/GO_0070678
• regulation of reactive oxygen species metabolic process
  http://purl.obolibrary.org/obo/GO_2000377

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map04722
• http://www.genome.jp/dbget-bin/www_bget?map05202

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cytokine-cytokine receptor interaction
• Neurotrophin signaling pathway
• Transcriptional misregulation in cancers