CD03361

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03361

CD03361

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Itpr1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• inositol 1,4,5-trisphosphate receptor 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• IP3R 1
• inositol 1,4,5-trisphosphate receptor type 1
• InsP>3<R type I
• inositol 1,4,5-triphosphate receptor 1
• type 1 InsP3 receptor
• Purkinje cell protein 1
• opisthotonus
• inositol 1,4,5-trisphosphate-binding protein P400
• insP3R1
• inositol 1,4,5-trisphosphate receptor 1
• protein PCD-6
• IP3 receptor
• type 1 inositol 1,4,5-trisphosphate receptor

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Pcp-1
• opt
• PCD-6
• InsP3R type I
• InsP3R1
• D6Pas2
• I145TR
• InsP3R
• Gm10429
• Pcp1
• Itpr-1
• Ip3r
• IP3R1
• P400
• ENSMUSG00000072853

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16438

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• inositol 1,4,5-trisphosphate receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96623

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010585

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000030102

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.227912

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=147265

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• C A. Ross, et.al., Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues., Proceedings of the National Academy of Sciences of the United States of America, 1992, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/1374893
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• T. Furuichi, et.al., Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400., Nature, 1989, 342
  http://rdf.ncbi.nlm.nih.gov/pubmed/2554142
• Jenny. Chan, et.al., Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20843799
• T. Nakagawa, et.al., The subtypes of the mouse inositol 1,4,5-trisphosphate receptor are expressed in a tissue-specific and developmentally specific manner., Proceedings of the National Academy of Sciences of the United States of America, 1991, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/1648733
• Danielle A. Sliter, et.al., Activated inositol 1,4,5-trisphosphate receptors are modified by homogeneous Lys-48- and Lys-63-linked ubiquitin chains, but only Lys-48-linked chains are required for degradation., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21071436
• Takayasu. Higo, et.al., Mechanism of ER stress-induced brain damage by IP(3) receptor., Neuron, 2010, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/21145001
• K. Mikoshiba, et.al., Primary structure and functional expression of the inositol 1,4,5-trisphosphate receptor, P400., Advances in experimental medicine and biology, 1991, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/1662017
• Keiko. Uchida, et.al., Gene knock-outs of inositol 1,4,5-trisphosphate receptors types 1 and 2 result in perturbation of cardiogenesis., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20824138
• D J. Norman, et.al., Genetic mapping of the lurcher locus on mouse chromosome 6 using an intersubspecific backcross., Genomics, 1991, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/1672287

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• endoplasmic reticulum membrane
  http://purl.obolibrary.org/obo/GO_0005789
• platelet dense granule membrane
  http://purl.obolibrary.org/obo/GO_0031088
• endoplasmic reticulum calcium ion homeostasis
  http://purl.obolibrary.org/obo/GO_0032469
• ion channel activity
  http://purl.obolibrary.org/obo/GO_0005216
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• voluntary musculoskeletal movement
  http://purl.obolibrary.org/obo/GO_0050882
• nuclear envelope
  http://purl.obolibrary.org/obo/GO_0005635
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• transmembrane transport
  http://purl.obolibrary.org/obo/GO_0055085
• post-embryonic development
  http://purl.obolibrary.org/obo/GO_0009791
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• nucleolus
  http://purl.obolibrary.org/obo/GO_0005730
• calcium ion transport
  http://purl.obolibrary.org/obo/GO_0006816
• membrane raft
  http://purl.obolibrary.org/obo/GO_0045121
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• platelet dense tubular network
  http://purl.obolibrary.org/obo/GO_0031094
• calcium channel activity
  http://purl.obolibrary.org/obo/GO_0005262
• ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034220
• calcium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0070588
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• microsome
  http://purl.obolibrary.org/obo/GO_0005792
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• calcium-release channel activity
  http://purl.obolibrary.org/obo/GO_0015278
• sarcoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0016529
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• calcineurin complex
  http://purl.obolibrary.org/obo/GO_0005955
• positive regulation of cytosolic calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0007204
• phosphatidylinositol binding
  http://purl.obolibrary.org/obo/GO_0035091
• secretory granule membrane
  http://purl.obolibrary.org/obo/GO_0030667
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• response to hypoxia
  http://purl.obolibrary.org/obo/GO_0001666
• postsynaptic density
  http://purl.obolibrary.org/obo/GO_0014069
• inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
  http://purl.obolibrary.org/obo/GO_0005220
• nuclear inner membrane
  http://purl.obolibrary.org/obo/GO_0005637
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04540
• http://www.genome.jp/dbget-bin/www_bget?map04270
• http://www.genome.jp/dbget-bin/www_bget?map05016
• http://www.genome.jp/dbget-bin/www_bget?map04720
• http://www.genome.jp/dbget-bin/www_bget?map04725
• http://www.genome.jp/dbget-bin/www_bget?map04020
• http://www.genome.jp/dbget-bin/www_bget?map04912
• http://www.genome.jp/dbget-bin/www_bget?map04070
• http://www.genome.jp/dbget-bin/www_bget?map04728
• http://www.genome.jp/dbget-bin/www_bget?map04972
• http://www.genome.jp/dbget-bin/www_bget?map04971
• http://www.genome.jp/dbget-bin/www_bget?map04114
• http://www.genome.jp/dbget-bin/www_bget?map04724
• http://www.genome.jp/dbget-bin/www_bget?map04970
• http://www.genome.jp/dbget-bin/www_bget?map04730
• http://www.genome.jp/dbget-bin/www_bget?map05010

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Long-term potentiation
• Vascular smooth muscle contraction
• Oocyte meiosis
• Alzheimer's disease
• Glutamatergic synapse
• Gap junction
• GnRH signaling pathway
• Pancreatic secretion
• Calcium signaling pathway
• Dopaminergic synapse
• Phosphatidylinositol signaling system
• Gastric acid secretion
• Cholinergic synapse
• Huntington's disease
• Salivary secretion
• Long-term depression