CD03427

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03427

CD03427

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Plat

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• plasminogen activator, tissue

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• t-plasminogen activator
• tissue-type plasminogen activator
• plasminogen activator, tissue

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• D8Ertd2e
• tPA
• AU020998
• t-PA
• AW212668

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18791

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• plasminogen activator, tissue
  http://metadb.riken.jp/db/mgi_rdf/MGI:97610

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_008872

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000031538

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.154660

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=173370

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Sha. Hao, et.al., tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20639453
• Ling. Lin, et.al., tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20724593
• A L. Boyle, et.al., Rapid physical mapping of cloned DNA on banded mouse chromosomes by fluorescence in situ hybridization., Genomics, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1733847
• Annika. Jögi, et.al., Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20856796
• T A. Howard, et.al., A linkage map of mouse chromosome 8: further definition of homologous linkage relationships between mouse chromosome 8 and human chromosomes 8, 16, and 19., Genomics, 1991, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/1675193
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• M P. Colombo, et.al., Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/1347472
• T. Kahn, et.al., Molecular cloning, analysis, and chromosomal localization of a mouse genomic sequence related to the human papillomavirus type 18 E5 region., Molecular carcinogenesis, 1992, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/1326990
• Jialing. Wu, et.al., Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20864675
• W N. Frankel, et.al., Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/B1NJ and SM/J inbred strains., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/1311971

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• secretory granule
  http://purl.obolibrary.org/obo/GO_0030141
• smooth muscle cell migration
  http://purl.obolibrary.org/obo/GO_0014909
• negative regulation of proteolysis
  http://purl.obolibrary.org/obo/GO_0045861
• synaptic transmission, glutamatergic
  http://purl.obolibrary.org/obo/GO_0035249
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• serine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004252
• response to hypoxia
  http://purl.obolibrary.org/obo/GO_0001666
• platelet-derived growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0048008
• plasminogen activation
  http://purl.obolibrary.org/obo/GO_0031639
• serine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008236
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• catalytic activity
  http://purl.obolibrary.org/obo/GO_0003824
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508
• apical part of cell
  http://purl.obolibrary.org/obo/GO_0045177
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04610
• http://www.genome.jp/dbget-bin/www_bget?map05202

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Complement and coagulation cascades
• Transcriptional misregulation in cancers