CD03763

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03763

CD03763

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ctsc

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• cathepsin C

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• dipeptidyl peptidase 1
• dipeptidyl transferase
• cathepsin C
• cathepsin J
• dipeptidyl peptidase I
• dipeptidyl-peptidase I
• dipeptidyl-peptidase 1
• DPP-I

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• DPPI
• DPP1
• dipeptidylpeptidase 1
• AI047818

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13032

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• cathepsin C
  http://metadb.riken.jp/db/mgi_rdf/MGI:109553

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009982

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000030560

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.322945

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602365

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Michael E. D'Angelo, et.al., Cathepsin H is an additional convertase of pro-granzyme B., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20435891
• Jennifer N. Lilla, et.al., Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis., Developmental biology, 2010, 337
  http://rdf.ncbi.nlm.nih.gov/pubmed/19850030
• Matthias. Regner, et.al., Cutting edge: rapid and efficient in vivo cytotoxicity by cytotoxic T cells is independent of granzymes A and B., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19525394
• M J. McGuire, et.al., Cloning and characterization of the cDNA encoding mouse dipeptidyl peptidase I (cathepsin C)., Biochimica et biophysica acta, 1997, 1351
  http://rdf.ncbi.nlm.nih.gov/pubmed/9130590
• N V. Rao, et.al., Human dipeptidyl-peptidase I. Gene characterization, localization, and expression., The Journal of biological chemistry, 1997, 272
  http://rdf.ncbi.nlm.nih.gov/pubmed/9092576
• Ingrid G. Winkler, et.al., Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20713966
• C T. Pham, et.al., Molecular cloning, chromosomal localization, and expression of murine dipeptidyl peptidase I., The Journal of biological chemistry, 1997, 272
  http://rdf.ncbi.nlm.nih.gov/pubmed/9099719
• A. Paris, et.al., Molecular cloning and sequence analysis of human preprocathepsin C., FEBS letters, 1995, 369
  http://rdf.ncbi.nlm.nih.gov/pubmed/7649281
• C T. Pham, et.al., Dipeptidyl peptidase I is required for the processing and activation of granzymes A and B in vivo., Proceedings of the National Academy of Sciences of the United States of America, 1999, 96
  http://rdf.ncbi.nlm.nih.gov/pubmed/10411926
• Vasilena. Gocheva, et.al., IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion., Genes & development, 2010, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/20080943

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• chloride ion binding
  http://purl.obolibrary.org/obo/GO_0031404
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• cysteine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0004197
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• response to organic substance
  http://purl.obolibrary.org/obo/GO_0010033
• peptidase activity
  http://purl.obolibrary.org/obo/GO_0008233
• protein self-association
  http://purl.obolibrary.org/obo/GO_0043621
• cysteine-type peptidase activity
  http://purl.obolibrary.org/obo/GO_0008234
• proteolysis
  http://purl.obolibrary.org/obo/GO_0006508

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04142

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Lysosome