CD03883

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03883

CD03883

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rcan1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• regulator of calcineurin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• myocyte-enriched calcineurin-interacting protein 1
• regulator of calcineurin 1
• Down syndrome critical region homolog 1
• down syndrome critical region protein 1 homolog
• calcipressin-1
• calcipressin 1
• calcineurin inhibitor
• myocyte-enriched calcineurin interactin protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• MCIP1
• RCN1
• CSP1
• Dscr1
• ADAPT78
• CALP1L
• AA408855
• AV028423
• AI429645
• Adapt78
• AL024459
• DSC1
• 2410048A02Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/54720

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• regulator of calcineurin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890564

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001081549
• https://www.ncbi.nlm.nih.gov/nuccore/NM_019466

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022951

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.265744

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602917

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Takashi. Minami, et.al., The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice., The Journal of clinical investigation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19620774
• Kwan-Hyuck. Baek, et.al., Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1., Nature, 2009, 459
  http://rdf.ncbi.nlm.nih.gov/pubmed/19458618
• B. Rothermel, et.al., A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10722714
• Grzegorz T. Gurda, et.al., Regulator of calcineurin 1 controls growth plasticity of adult pancreas., Gastroenterology, 2010, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/20438729
• C. Casas, et.al., Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis., Mechanisms of development, 2001, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/11231093
• Monica Y. Lee, et.al., Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells., Human molecular genetics, 2010, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/19926569
• P. Strippoli, et.al., The murine DSCR1-like (Down syndrome candidate region 1) gene family: conserved synteny with the human orthologous genes., Gene, 2000, 257
  http://rdf.ncbi.nlm.nih.gov/pubmed/11080588
• Alexandre. Reymond, et.al., Human chromosome 21 gene expression atlas in the mouse., Nature, 2002, 420
  http://rdf.ncbi.nlm.nih.gov/pubmed/12466854
• P. Strippoli, et.al., A new gene family including DSCR1 (Down Syndrome Candidate Region 1) and ZAKI-4: characterization from yeast to human and identification of DSCR1-like 2, a novel human member (DSCR1L2)., Genomics, 2000, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/10756093
• Misook. Oh, et.al., The CCAAT/enhancer binding protein beta (C/EBPbeta) cooperates with NFAT to control expression of the calcineurin regulatory protein RCAN1-4., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20371871

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• regulation of phosphoprotein phosphatase activity
  http://purl.obolibrary.org/obo/GO_0043666
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• skeletal muscle fiber development
  http://purl.obolibrary.org/obo/GO_0048741
• response to estrogen
  http://purl.obolibrary.org/obo/GO_0043627
• calcium-mediated signaling
  http://purl.obolibrary.org/obo/GO_0019722
• negative regulation of smooth muscle cell differentiation
  http://purl.obolibrary.org/obo/GO_0051151
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName