CD04061

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04061

CD04061

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pcsk1n

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• proprotein convertase subtilisin/kexin type 1 inhibitor

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• big SAAS
• granin-like neuroendocrine peptide
• proprotein convertase subtilisin/kexin type 1 inhibitor
• big PEN LEN
• little LEN
• proprotein convertase 1 inhibitor
• IA-4
• protein serine alanine alanine serine
• little SAAS
• pro-SAAS
• pancreas protein 3

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• PEN19
• Pan3
• SAASCT
• basic protein IA-4
• SAAS
• proSAAS
• lLEN
• AI848336
• PEN20
• bLEN
• PEN
• KEP

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/30052

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• proprotein convertase subtilisin/kexin type 1 inhibitor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353431

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_013892

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000039278

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.4881

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=300399

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Sayah, et.al., Tissue distribution and processing of proSAAS by proprotein convertases., Journal of neurochemistry, 2001, 76
  http://rdf.ncbi.nlm.nih.gov/pubmed/11259501
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821
• Carly. St Germain, et.al., Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development., Molecular reproduction and development, 2005, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/16163737
• L D. Fricker, et.al., Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/10632593
• E. Apletalina, et.al., Identification of inhibitors of prohormone convertases 1 and 2 using a peptide combinatorial library., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9756897
• G. Donadel, et.al., Molecular cloning and characterization of a highly basic protein, IA-4, expressed in pancreatic islets and brain., Neuroendocrinology, 1998, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/9630436
• N. Mzhavia, et.al., ProSAAS processing in mouse brain and pituitary., The Journal of biological chemistry, 2001, 276
  http://rdf.ncbi.nlm.nih.gov/pubmed/11094058
• Tandra R. Chakraborty, et.al., Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress., Brain research, 2006, 1089
  http://rdf.ncbi.nlm.nih.gov/pubmed/16631141
• Daniel J. Morgan, et.al., The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation., Journal of neurochemistry, 2010, 113
  http://rdf.ncbi.nlm.nih.gov/pubmed/20367757

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• negative regulation of endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0010951
• neuropeptide signaling pathway
  http://purl.obolibrary.org/obo/GO_0007218
• trans-Golgi network
  http://purl.obolibrary.org/obo/GO_0005802
• secretory granule
  http://purl.obolibrary.org/obo/GO_0030141
• peptide hormone processing
  http://purl.obolibrary.org/obo/GO_0016486
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• serine-type endopeptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0004867
• response to cold
  http://purl.obolibrary.org/obo/GO_0009409
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• endopeptidase inhibitor activity
  http://purl.obolibrary.org/obo/GO_0004866
• response to dietary excess
  http://purl.obolibrary.org/obo/GO_0002021

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName