CD04484

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04484

CD04484

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ulk2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• Unc-51 like kinase 2 (C. elegans)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• serine/threonine-protein kinase ULK2
• Unc-51 like kinase 2 (C. elegans)
• serine/threonine-protein kinase Unc51.2
• unc-51-like kinase 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AU015340
• A830085I22Rik
• Unc51.2
• mKIAA0623

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/29869

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• unc-51 like kinase 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352758

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_013881

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000004798

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.162025

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608650

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Taichi. Hara, et.al., FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells., The Journal of cell biology, 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18443221
• T. Tomoda, et.al., A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons., Neuron, 1999, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/10624947
• Jiong. Yan, et.al., Penetrance of craniofacial anomalies in mouse models of Smith-Magenis syndrome is modified by genomic sequence surrounding Rai1: not all null alleles are alike., American journal of human genetics, 2007, 80
  http://rdf.ncbi.nlm.nih.gov/pubmed/17273973
• J. Yan, et.al., Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains., Oncogene, 1999, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/10557072
• Xiang. Zhou, et.al., Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons., Proceedings of the National Academy of Sciences of the United States of America, 2007, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/17389358
• J. Yan, et.al., Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51., Biochemical and biophysical research communications, 1998, 246
  http://rdf.ncbi.nlm.nih.gov/pubmed/9600096
• Edmond Y W. Chan, et.al., Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/18936157
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Y. Piao, et.al., Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method., Genome research, 2001, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/11544199
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2003, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/12693553

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• macroautophagy
  http://purl.obolibrary.org/obo/GO_0016236
• negative regulation of collateral sprouting
  http://purl.obolibrary.org/obo/GO_0048671
• protein serine/threonine kinase activity
  http://purl.obolibrary.org/obo/GO_0004674
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0006468
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• response to starvation
  http://purl.obolibrary.org/obo/GO_0042594
• axonogenesis
  http://purl.obolibrary.org/obo/GO_0007409
• protein kinase activity
  http://purl.obolibrary.org/obo/GO_0004672
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• protein autophosphorylation
  http://purl.obolibrary.org/obo/GO_0046777
• autophagy
  http://purl.obolibrary.org/obo/GO_0006914
• cytoplasmic vesicle
  http://purl.obolibrary.org/obo/GO_0031410
• nervous system development
  http://purl.obolibrary.org/obo/GO_0007399
• axon extension
  http://purl.obolibrary.org/obo/GO_0048675
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• pre-autophagosomal structure membrane
  http://purl.obolibrary.org/obo/GO_0034045
• regulation of autophagy
  http://purl.obolibrary.org/obo/GO_0010506

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04150
• http://www.genome.jp/dbget-bin/www_bget?map04140

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• mTOR signaling pathway
• Regulation of autophagy