CD04705

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04705

CD04705

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tnfsf13

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• tumor necrosis factor (ligand) superfamily, member 13

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• a proliferation-inducing ligand
• tumor necrosis factor ligand superfamily member 13
• tumor necrosis factor (ligand) superfamily, member 13

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Tall2
• April
• 2310026N09Rik
• Trdl1
• TALL2
• TRDL1
• APRIL

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/69583

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• tumor necrosis factor (ligand) superfamily, member 13
  http://metadb.riken.jp/db/mgi_rdf/MGI:1916833

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_023517
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001159505

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000089669

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.8983

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604472

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Yanping. Xiao, et.al., APRIL (TNFSF13) regulates collagen-induced arthritis, IL-17 production and Th2 response., European journal of immunology, 2008, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/19016524
• Ian. MacLennan, et.al., Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses., Immunity, 2002, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12354377
• Eugene. Varfolomeev, et.al., APRIL-deficient mice have normal immune system development., Molecular and cellular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/14729948
• Young-Saeng. Jang, et.al., IL-4 stimulates mouse macrophages to express APRIL through p38MAPK and two different downstream molecules, CREB and Stat6., Cytokine, 2009, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/19427796
• G. Yu, et.al., APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity., Nature immunology, 2000, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/10973284
• R M. Locksley, et.al., The TNF and TNF receptor superfamilies: integrating mammalian biology., Cell, 2001, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/11239407
• Van Trung. Chu, et.al., Eosinophils are required for the maintenance of plasma cells in the bone marrow., Nature immunology, 2011, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/21217761
• Jens V. Stein, et.al., APRIL modulates B and T cell immunity., The Journal of clinical investigation, 2002, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/12070306
• Yanping. Xiao, et.al., TNF superfamily member 13, APRIL, inhibits allergic lung inflammation., European journal of immunology, 2011, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/21182087
• J. Bilsborough, et.al., TACI-Ig prevents the development of airway hyperresponsiveness in a murine model of asthma., Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2008, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/19037968

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of germinal center formation
  http://purl.obolibrary.org/obo/GO_0002636
• regulation of immune response
  http://purl.obolibrary.org/obo/GO_0050776
• cytokine activity
  http://purl.obolibrary.org/obo/GO_0005125
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• positive regulation of isotype switching to IgA isotypes
  http://purl.obolibrary.org/obo/GO_0048298
• immunoglobulin mediated immune response
  http://purl.obolibrary.org/obo/GO_0016064
• immunoglobulin production in mucosal tissue
  http://purl.obolibrary.org/obo/GO_0002426
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• tumor necrosis factor receptor binding
  http://purl.obolibrary.org/obo/GO_0005164
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04060
• http://www.genome.jp/dbget-bin/www_bget?map05323
• http://www.genome.jp/dbget-bin/www_bget?map04672

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Rheumatoid arthritis
• Intestinal immune network for IgA production
• Cytokine-cytokine receptor interaction