CD04797

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04797

CD04797

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Tnfrsf12a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• tumor necrosis factor receptor superfamily, member 12a

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• fibroblast growth factor regulated protein 2
• fibroblast growth factor-inducible immediate-early response protein 14
• fibroblast growth factor-regulated protein 2
• tweak-receptor
• tumor necrosis factor receptor superfamily, member 12a
• tumor necrosis factor receptor superfamily member 12A
• type I transmembrane protein Fn14
• FGF-inducible 14

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• C87282
• TweakR
• TWEAK-R
• HPIP
• Fn14
• AI255180

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/27279

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• tumor necrosis factor receptor superfamily, member 12a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1351484

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001161746
• https://www.ncbi.nlm.nih.gov/nuccore/NM_013749

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000023905

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.28518

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605914

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• R L. Meighan-Mantha, et.al., The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10551889
• Sharron A N. Brown, et.al., The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation., The Biochemical journal, 2003, 371
  http://rdf.ncbi.nlm.nih.gov/pubmed/12529173
• Woldeab B. Haile, et.al., The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain., Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20068578
• Ashwani. Mittal, et.al., The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice., The Journal of cell biology, 2010, 188
  http://rdf.ncbi.nlm.nih.gov/pubmed/20308426
• S L. Feng, et.al., The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas., The American journal of pathology, 2000, 156
  http://rdf.ncbi.nlm.nih.gov/pubmed/10751351
• Mohit. Jain, et.al., A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure., Circulation, 2009, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/19349318
• John C. Reed, et.al., Comparative analysis of apoptosis and inflammation genes of mice and humans., Genome research, 2003, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/12819136
• Tara C. Polek, et.al., TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12794080
• Alberto. Molano, et.al., TWEAK stimulation of kidney resident cells in the pathogenesis of graft versus host induced lupus nephritis., Immunology letters, 2009, 125
  http://rdf.ncbi.nlm.nih.gov/pubmed/19573558

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cargo receptor activity
  http://purl.obolibrary.org/obo/GO_0038024
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• ruffle
  http://purl.obolibrary.org/obo/GO_0001726
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• angiogenesis
  http://purl.obolibrary.org/obo/GO_0001525
• cell death
  http://purl.obolibrary.org/obo/GO_0008219
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• substrate-dependent cell migration, cell attachment to substrate
  http://purl.obolibrary.org/obo/GO_0006931
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• signaling receptor activity
  http://purl.obolibrary.org/obo/GO_0038023
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of axon extension
  http://purl.obolibrary.org/obo/GO_0045773

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04060

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cytokine-cytokine receptor interaction