CD04943

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04943

CD04943

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Bak1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• BCL2-antagonist/killer 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• Bcl2 homologous antagonist/killer
• apoptosis regulator BAK
• bcl-2 homologous antagonist/killer
• BCL2-antagonist/killer 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• N-BAK1
• N-Bak
• Bak

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12018

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• BCL2-antagonist/killer 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097161

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007523

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000057789

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2443

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600516

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• S N. Farrow, et.al., Cloning of a bcl-2 homologue by interaction with adenovirus E1B 19K., Nature, 1995, 374
  http://rdf.ncbi.nlm.nih.gov/pubmed/7715729
• M C. Kiefer, et.al., Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak., Nature, 1995, 374
  http://rdf.ncbi.nlm.nih.gov/pubmed/7715731
• S P. Tzung, et.al., Expression of Bcl-2 family during liver regeneration and identification of Bcl-x as a delayed early response gene., The American journal of pathology, 1997, 150
  http://rdf.ncbi.nlm.nih.gov/pubmed/9176392
• http://rdf.ncbi.nlm.nih.gov/pubmed/20799797
• T. Chittenden, et.al., A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions., The EMBO journal, 1995, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/8521816
• Pablo M. Peixoto, et.al., Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect., The American journal of pathology, 2011, 178
  http://rdf.ncbi.nlm.nih.gov/pubmed/21224042
• Decheng. Ren, et.al., BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program., Science (New York, N.Y.), 2010, 330
  http://rdf.ncbi.nlm.nih.gov/pubmed/21127253
• T. Chittenden, et.al., Induction of apoptosis by the Bcl-2 homologue Bak., Nature, 1995, 374
  http://rdf.ncbi.nlm.nih.gov/pubmed/7715730
• Nichole A. Reyes, et.al., Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20890041
• Subhrajit. Biswas, et.al., A role for proapoptotic Bax and Bak in T-cell differentiation and transformation., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20813900

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• B cell homeostasis
  http://purl.obolibrary.org/obo/GO_0001782
• response to mycotoxin
  http://purl.obolibrary.org/obo/GO_0010046
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• regulation of mitochondrial membrane permeability
  http://purl.obolibrary.org/obo/GO_0046902
• post-embryonic camera-type eye morphogenesis
  http://purl.obolibrary.org/obo/GO_0048597
• response to gamma radiation
  http://purl.obolibrary.org/obo/GO_0010332
• activation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0006919
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• positive regulation of calcium ion transport into cytosol
  http://purl.obolibrary.org/obo/GO_0010524
• negative regulation of peptidyl-serine phosphorylation
  http://purl.obolibrary.org/obo/GO_0033137
• mitochondrial fusion
  http://purl.obolibrary.org/obo/GO_0008053
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• pore complex
  http://purl.obolibrary.org/obo/GO_0046930
• BH domain binding
  http://purl.obolibrary.org/obo/GO_0051400
• positive regulation of release of cytochrome c from mitochondria
  http://purl.obolibrary.org/obo/GO_0090200
• myeloid cell homeostasis
  http://purl.obolibrary.org/obo/GO_0002262
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• leukocyte homeostasis
  http://purl.obolibrary.org/obo/GO_0001776
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0046982
• vagina development
  http://purl.obolibrary.org/obo/GO_0060068
• activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
  http://purl.obolibrary.org/obo/GO_0008635
• establishment or maintenance of transmembrane electrochemical gradient
  http://purl.obolibrary.org/obo/GO_0010248
• cellular response to UV
  http://purl.obolibrary.org/obo/GO_0034644
• response to fungus
  http://purl.obolibrary.org/obo/GO_0009620
• limb morphogenesis
  http://purl.obolibrary.org/obo/GO_0035108
• B cell apoptotic process
  http://purl.obolibrary.org/obo/GO_0001783
• regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0042981
• positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
  http://purl.obolibrary.org/obo/GO_0043280
• negative regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010629
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• apoptotic signaling pathway
  http://purl.obolibrary.org/obo/GO_0097190
• negative regulation of endoplasmic reticulum calcium ion concentration
  http://purl.obolibrary.org/obo/GO_0032471
• mitochondrion
  http://purl.obolibrary.org/obo/GO_0005739
• homeostasis of number of cells
  http://purl.obolibrary.org/obo/GO_0048872
• cell proliferation
  http://purl.obolibrary.org/obo/GO_0008283
• regulation of mitochondrial membrane potential
  http://purl.obolibrary.org/obo/GO_0051881
• mitochondrial membrane
  http://purl.obolibrary.org/obo/GO_0031966
• release of cytochrome c from mitochondria
  http://purl.obolibrary.org/obo/GO_0001836
• regulation of cell cycle
  http://purl.obolibrary.org/obo/GO_0051726
• regulation of protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0043496
• B cell negative selection
  http://purl.obolibrary.org/obo/GO_0002352
• intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
  http://purl.obolibrary.org/obo/GO_0070059
• positive regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043065
• heat shock protein binding
  http://purl.obolibrary.org/obo/GO_0031072
• activation of cysteine-type endopeptidase activity
  http://purl.obolibrary.org/obo/GO_0097202
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• blood vessel remodeling
  http://purl.obolibrary.org/obo/GO_0001974
• chaperone binding
  http://purl.obolibrary.org/obo/GO_0051087
• regulation of protein heterodimerization activity
  http://purl.obolibrary.org/obo/GO_0043497
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04141

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Protein processing in endoplasmic reticulum