CD05108

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05108

CD05108

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rela

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• v-rel reticuloendotheliosis viral oncogene homolog A (avian)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• p65 NFkB
• transcription factor p65
• p65 NF-kappa B
• nuclear factor NF-kappa-B p65 subunit
• nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
• avian reticuloendotheliosis viral (v-rel) oncogene homolog A
• v-rel reticuloendotheliosis viral oncogene homolog A (avian)

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• p65 NF kappaB
• p65

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/19697

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• v-rel reticuloendotheliosis viral oncogene homolog A (avian)
  http://metadb.riken.jp/db/mgi_rdf/MGI:103290

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009045

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024927

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.249966

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=164014

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Wei. Zhao, et.al., NF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21257959
• I M. Verma, et.al., Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation., Genes & development, 1995, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/7590248
• Emily E. Rosowski, et.al., Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein., The Journal of experimental medicine, 2011, 208
  http://rdf.ncbi.nlm.nih.gov/pubmed/21199955
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• L. Guerrini, et.al., Synaptic activation of NF-kappa B by glutamate in cerebellar granule neurons in vitro., Proceedings of the National Academy of Sciences of the United States of America, 1995, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/7568076
• S M. Dunn, et.al., Requirement for nuclear factor (NF)-kappa B p65 and NF-interleukin-6 binding elements in the tumor necrosis factor response region of the granulocyte colony-stimulating factor promoter., Blood, 1994, 83
  http://rdf.ncbi.nlm.nih.gov/pubmed/7513199
• G P. Nolan, et.al., DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide., Cell, 1991, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/2001591
• Carl Y. Sasaki, et.al., Recruitment of RelB to the Csf2 promoter enhances RelA-mediated transcription of granulocyte-macrophage colony-stimulating factor., The Journal of biological chemistry, 2011, 286
  http://rdf.ncbi.nlm.nih.gov/pubmed/21071440
• Susan F. Fitzpatrick, et.al., An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21149600
• A A. Beg, et.al., Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B., Nature, 1995, 376
  http://rdf.ncbi.nlm.nih.gov/pubmed/7603567

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• macromolecular complex binding
  http://purl.obolibrary.org/obo/GO_0044877
• response to bacterium
  http://purl.obolibrary.org/obo/GO_0009617
• ankyrin repeat binding
  http://purl.obolibrary.org/obo/GO_0071532
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• positive regulation of Schwann cell differentiation
  http://purl.obolibrary.org/obo/GO_0014040
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• chromatin binding
  http://purl.obolibrary.org/obo/GO_0003682
• activating transcription factor binding
  http://purl.obolibrary.org/obo/GO_0033613
• cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0019221
• regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050727
• identical protein binding
  http://purl.obolibrary.org/obo/GO_0042802
• positive regulation of NF-kappaB transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051092
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003705
• response to interleukin-1
  http://purl.obolibrary.org/obo/GO_0070555
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• positive regulation of interleukin-12 biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045084
• NF-kappaB binding
  http://purl.obolibrary.org/obo/GO_0051059
• positive regulation of chondrocyte differentiation
  http://purl.obolibrary.org/obo/GO_0032332
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• transcription factor complex
  http://purl.obolibrary.org/obo/GO_0005667
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• response to muramyl dipeptide
  http://purl.obolibrary.org/obo/GO_0032495
• response to UV-B
  http://purl.obolibrary.org/obo/GO_0010224
• phosphate ion binding
  http://purl.obolibrary.org/obo/GO_0042301
• macromolecular complex
  http://purl.obolibrary.org/obo/GO_0032991
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• hair follicle development
  http://purl.obolibrary.org/obo/GO_0001942
• nucleotide-binding oligomerization domain containing 2 signaling pathway
  http://purl.obolibrary.org/obo/GO_0070431
• response to organic substance
  http://purl.obolibrary.org/obo/GO_0010033
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• transcription factor binding
  http://purl.obolibrary.org/obo/GO_0008134
• protein N-terminus binding
  http://purl.obolibrary.org/obo/GO_0047485
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• negative regulation of insulin receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0046627
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• repressing transcription factor binding
  http://purl.obolibrary.org/obo/GO_0070491
• defense response
  http://purl.obolibrary.org/obo/GO_0006952
• negative regulation of protein catabolic process
  http://purl.obolibrary.org/obo/GO_0042177
• liver development
  http://purl.obolibrary.org/obo/GO_0001889
• ubiquitin protein ligase binding
  http://purl.obolibrary.org/obo/GO_0031625

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05132
• http://www.genome.jp/dbget-bin/www_bget?map04623
• http://www.genome.jp/dbget-bin/www_bget?map05168
• http://www.genome.jp/dbget-bin/www_bget?map05215
• http://www.genome.jp/dbget-bin/www_bget?map04380
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map05212
• http://www.genome.jp/dbget-bin/www_bget?map05145
• http://www.genome.jp/dbget-bin/www_bget?map04722
• http://www.genome.jp/dbget-bin/www_bget?map05142
• http://www.genome.jp/dbget-bin/www_bget?map05134
• http://www.genome.jp/dbget-bin/www_bget?map05140
• http://www.genome.jp/dbget-bin/www_bget?map05220
• http://www.genome.jp/dbget-bin/www_bget?map04622
• http://www.genome.jp/dbget-bin/www_bget?map05146
• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map04920
• http://www.genome.jp/dbget-bin/www_bget?map05160
• http://www.genome.jp/dbget-bin/www_bget?map04621
• http://www.genome.jp/dbget-bin/www_bget?map05222
• http://www.genome.jp/dbget-bin/www_bget?map05133
• http://www.genome.jp/dbget-bin/www_bget?map05152
• http://www.genome.jp/dbget-bin/www_bget?map05164
• http://www.genome.jp/dbget-bin/www_bget?map04062
• http://www.genome.jp/dbget-bin/www_bget?map04210
• http://www.genome.jp/dbget-bin/www_bget?map04662
• http://www.genome.jp/dbget-bin/www_bget?map05202
• http://www.genome.jp/dbget-bin/www_bget?map05162
• http://www.genome.jp/dbget-bin/www_bget?map04620
• http://www.genome.jp/dbget-bin/www_bget?map04660
• http://www.genome.jp/dbget-bin/www_bget?map05221

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Toxoplasmosis
• MAPK signaling pathway
• HTLV-I infection
• Small cell lung cancer
• Transcriptional misregulation in cancers
• Tuberculosis
• Chronic myeloid leukemia
• Apoptosis
• Adipocytokine signaling pathway
• NOD-like receptor signaling pathway
• T cell receptor signaling pathway
• Pathways in cancer
• Prostate cancer
• Hepatitis C
• RIG-I-like receptor signaling pathway
• Chemokine signaling pathway
• Herpes simplex infection
• Pertussis
• B cell receptor signaling pathway
• Cytosolic DNA-sensing pathway
• Legionellosis
• Osteoclast differentiation
• Leishmaniasis
• Neurotrophin signaling pathway
• Toll-like receptor signaling pathway
• Chagas disease (American trypanosomiasis)
• Acute myeloid leukemia
• Salmonella infection
• Influenza A
• Measles
• Amoebiasis
• Pancreatic cancer