CD05240

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05240

CD05240

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Slc11a1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
• NRAMP 1
• natural resistance-associated macrophage protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• ity
• host resistance locus Bcg/Ity/Lsh
• Bcg
• Nramp
• Nramp1
• Lsh
• Ity

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18173

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345275

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_013612

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000026177

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2913

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600266

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Maroof. Husain, et.al., Redox sensor SsrB Cys203 enhances Salmonella fitness against nitric oxide generated in the host immune response to oral infection., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20660761
• Shan. Soe-Lin, et.al., Both Nramp1 and DMT1 are necessary for efficient macrophage iron recycling., Experimental hematology, 2010, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/20394798
• D J. Bradley, Regulation of Leishmania populations within the host. II. genetic control of acute susceptibility of mice to Leishmania donovani infection., Clinical and experimental immunology, 1977, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/606434
• D J. Bradley, et.al., Regulation of Leishmania populations within the host. III. Mapping of the locus controlling susceptibility to visceral leishmaniasis in the mouse., Clinical and experimental immunology, 1979, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/290436
• J. Plant, et.al., Locating salmonella resistance gene on mouse chromosome 1., Clinical and experimental immunology, 1979, 37
  http://rdf.ncbi.nlm.nih.gov/pubmed/385184
• C H. Barton, et.al., Mapping Creb-1 to chromosome 1 in the mouse., Genomics, 1992, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/1358811
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Robert W. Crawford, et.al., Gallstones play a significant role in Salmonella spp. gallbladder colonization and carriage., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20176950
• J. Plant, et.al., Genetics of resistance to infection with Salmonella typhimurium in mice., The Journal of infectious diseases, 1976, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/1107437
• Etienne. Richer, et.al., N-ethyl-N-nitrosourea-induced mutation in ubiquitin-specific peptidase 18 causes hyperactivation of IFN-αß signaling and suppresses STAT4-induced IFN-γ production, resulting in increased susceptibility to Salmonella typhimurium., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20693420

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of interferon-gamma production
  http://purl.obolibrary.org/obo/GO_0032729
• response to interferon-gamma
  http://purl.obolibrary.org/obo/GO_0034341
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• tertiary granule membrane
  http://purl.obolibrary.org/obo/GO_0070821
• mRNA stabilization
  http://purl.obolibrary.org/obo/GO_0048255
• metal ion:proton antiporter activity
  http://purl.obolibrary.org/obo/GO_0051139
• inflammatory response
  http://purl.obolibrary.org/obo/GO_0006954
• iron ion homeostasis
  http://purl.obolibrary.org/obo/GO_0055072
• divalent metal ion export
  http://purl.obolibrary.org/obo/GO_0070839
• interleukin-3 production
  http://purl.obolibrary.org/obo/GO_0032632
• L-arginine transport
  http://purl.obolibrary.org/obo/GO_1902023
• macrophage activation
  http://purl.obolibrary.org/obo/GO_0042116
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• defense response to protozoan
  http://purl.obolibrary.org/obo/GO_0042832
• negative regulation of cytokine production
  http://purl.obolibrary.org/obo/GO_0001818
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• manganese ion transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0005384
• hydrogen ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_1902600
• cellular cadmium ion homeostasis
  http://purl.obolibrary.org/obo/GO_0006876
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• MHC class II biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045342
• response to lipopolysaccharide
  http://purl.obolibrary.org/obo/GO_0032496
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• positive regulation of T-helper 1 type immune response
  http://purl.obolibrary.org/obo/GO_0002827
• positive regulation of phagocytosis
  http://purl.obolibrary.org/obo/GO_0050766
• cadmium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0070574
• response to bacterium
  http://purl.obolibrary.org/obo/GO_0009617
• interleukin-2 production
  http://purl.obolibrary.org/obo/GO_0032623
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• transporter activity
  http://purl.obolibrary.org/obo/GO_0005215
• antigen processing and presentation of peptide antigen
  http://purl.obolibrary.org/obo/GO_0048002
• activation of protein kinase activity
  http://purl.obolibrary.org/obo/GO_0032147
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764
• phagocytic vesicle membrane
  http://purl.obolibrary.org/obo/GO_0030670
• transition metal ion transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0046915
• T cell proliferation involved in immune response
  http://purl.obolibrary.org/obo/GO_0002309
• vacuole
  http://purl.obolibrary.org/obo/GO_0005773
• positive regulation of cytokine production
  http://purl.obolibrary.org/obo/GO_0001819
• vacuolar acidification
  http://purl.obolibrary.org/obo/GO_0007035
• MAPK cascade
  http://purl.obolibrary.org/obo/GO_0000165
• defense response to Gram-negative bacterium
  http://purl.obolibrary.org/obo/GO_0050829
• manganese ion transport
  http://purl.obolibrary.org/obo/GO_0006828
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• multicellular organismal iron ion homeostasis
  http://purl.obolibrary.org/obo/GO_0060586
• late endosome
  http://purl.obolibrary.org/obo/GO_0005770
• positive regulation of dendritic cell antigen processing and presentation
  http://purl.obolibrary.org/obo/GO_0002606
• endosome membrane
  http://purl.obolibrary.org/obo/GO_0010008
• cellular iron ion homeostasis
  http://purl.obolibrary.org/obo/GO_0006879
• respiratory burst
  http://purl.obolibrary.org/obo/GO_0045730
• protein import into nucleus, translocation
  http://purl.obolibrary.org/obo/GO_0000060
• iron ion transport
  http://purl.obolibrary.org/obo/GO_0006826
• wound healing
  http://purl.obolibrary.org/obo/GO_0042060
• T cell cytokine production
  http://purl.obolibrary.org/obo/GO_0002369
• defense response to bacterium
  http://purl.obolibrary.org/obo/GO_0042742
• phagocytosis
  http://purl.obolibrary.org/obo/GO_0006909
• cell outer membrane
  http://purl.obolibrary.org/obo/GO_0009279
• nitrite transport
  http://purl.obolibrary.org/obo/GO_0015707
• transport
  http://purl.obolibrary.org/obo/GO_0006810

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04978
• http://www.genome.jp/dbget-bin/www_bget?map04142

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Lysosome
• Mineral absorption