CD05273

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05273

CD05273

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Dab2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• disabled homolog 2 (Drosophila)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• mitogen-responsive phosphoprotein
• disabled homolog 2 (Drosophila)
• disabled homolog 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Doc2
• 5730435J12Rik
• AI957090
• Doc-2
• D630005B22Rik
• p96
• D15Wsu122e
• AA960054

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/13132

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• disabled 2, mitogen-responsive phosphoprotein
  http://metadb.riken.jp/db/mgi_rdf/MGI:109175

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001008702
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001102400
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001037905
• https://www.ncbi.nlm.nih.gov/nuccore/NM_023118

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022150;%20ENSMUSG00000079102

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.240830

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601236

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M S. Ko, et.al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome., Human molecular genetics, 1998, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/9811942
• Nitya. Jain, et.al., Cutting edge: Dab2 is a FOXP3 target gene required for regulatory T cell function., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19767570
• Yukiko. Hasumi, et.al., Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19850877
• Anne. Collaco, et.al., Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20351096
• R R. Duncan, et.al., Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/10488064
• E E. Morrisey, et.al., The gene encoding the mitogen-responsive phosphoprotein Dab2 is differentially regulated by GATA-6 and GATA-4 in the visceral endoderm., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10779506
• X X. Xu, et.al., Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7775479
• S Y. Cho, et.al., Differential expression of mouse Disabled 2 gene in retinoic acid-treated F9 embryonal carcinoma cells and early mouse embryos., Molecules and cells, 1999, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10340473
• Arindam. Chaudhury, et.al., TGF-beta-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI., Nature cell biology, 2010, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/20154680
• Sumedha G. Penheiter, et.al., Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2., Molecular biology of the cell, 2010, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/20881059

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of protein phosphorylation
  http://purl.obolibrary.org/obo/GO_0001934
• pinocytosis
  http://purl.obolibrary.org/obo/GO_0006907
• coated pit
  http://purl.obolibrary.org/obo/GO_0005905
• excretion
  http://purl.obolibrary.org/obo/GO_0007588
• positive regulation of Wnt signaling pathway, planar cell polarity pathway
  http://purl.obolibrary.org/obo/GO_2000096
• cytoplasmic vesicle
  http://purl.obolibrary.org/obo/GO_0031410
• cell morphogenesis involved in differentiation
  http://purl.obolibrary.org/obo/GO_0000904
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• protein C-terminus binding
  http://purl.obolibrary.org/obo/GO_0008022
• positive regulation of proteasomal ubiquitin-dependent protein catabolic process
  http://purl.obolibrary.org/obo/GO_0032436
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• negative regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0090090
• negative regulation of cell growth
  http://purl.obolibrary.org/obo/GO_0030308
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• in utero embryonic development
  http://purl.obolibrary.org/obo/GO_0001701
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• negative regulation of protein binding
  http://purl.obolibrary.org/obo/GO_0032091
• receptor-mediated endocytosis
  http://purl.obolibrary.org/obo/GO_0006898
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Endocytosis