CD05711

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05711

CD05711

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Mad2l1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• MAD2 mitotic arrest deficient-like 1 (yeast)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• mitotic arrest deficient 2-like protein 1
• MAD2 (mitotic arrest deficient, homolog)-like 1
• mitotic spindle assembly checkpoint protein MAD2A
• MAD2-like protein 1
• MAD2 mitotic arrest deficient-like 1 (yeast)

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• MAD2
• AA673185

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/56150

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• MAD2 mitotic arrest deficient-like 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860374

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_019499

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029910

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.485053

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=601467

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Dobles, et.al., Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2., Cell, 2000, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/10892650
• Teruo. Nakaya, et.al., Critical role of Pcid2 in B cell survival through the regulation of MAD2 expression., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20870947
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• M A. Farmer, et.al., A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice., Proceedings of the National Academy of Sciences of the United States of America, 2001, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/11707574
• M. Kallio, et.al., Differences in spindle association of the mitotic checkpoint protein Mad2 in mammalian spermatogenesis and oogenesis., Developmental biology, 2000, 225
  http://rdf.ncbi.nlm.nih.gov/pubmed/10964468
• Rumana. Bahar, et.al., Growth retardation, polyploidy, and multinucleation induced by Clast3, a novel cell cycle-regulated protein., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/12147697
• L S. Michel, et.al., MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells., Nature, 2001, 409
  http://rdf.ncbi.nlm.nih.gov/pubmed/11201745
• Ya-Hui. Chi, et.al., Spindle assembly checkpoint and p53 deficiencies cooperate for tumorigenesis in mice., International journal of cancer, 2009, 124
  http://rdf.ncbi.nlm.nih.gov/pubmed/19065665
• Rocio. Sotillo, et.al., Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawal., Nature, 2010, 464
  http://rdf.ncbi.nlm.nih.gov/pubmed/20173739
• Ping. Zheng, et.al., Role of Filia, a maternal effect gene, in maintaining euploidy during cleavage-stage mouse embryogenesis., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19376971

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• mitotic cell cycle checkpoint
  http://purl.obolibrary.org/obo/GO_0007093
• mitotic spindle assembly checkpoint
  http://purl.obolibrary.org/obo/GO_0007094
• perinuclear region of cytoplasm
  http://purl.obolibrary.org/obo/GO_0048471
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• negative regulation of protein catabolic process
  http://purl.obolibrary.org/obo/GO_0042177
• http://purl.obolibrary.org/obo/GO_1904667
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• positive regulation of mitotic cell cycle spindle assembly checkpoint
  http://purl.obolibrary.org/obo/GO_0090267
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• mitotic sister chromatid segregation
  http://purl.obolibrary.org/obo/GO_0000070
• chromosome
  http://purl.obolibrary.org/obo/GO_0005694
• mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0000278
• chromosome, centromeric region
  http://purl.obolibrary.org/obo/GO_0000775
• kinetochore
  http://purl.obolibrary.org/obo/GO_0000776
• negative regulation of mitotic metaphase/anaphase transition
  http://purl.obolibrary.org/obo/GO_0045841
• spindle pole
  http://purl.obolibrary.org/obo/GO_0000922
• cell division
  http://purl.obolibrary.org/obo/GO_0051301
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04114
• http://www.genome.jp/dbget-bin/www_bget?map04110
• http://www.genome.jp/dbget-bin/www_bget?map04914

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Cell cycle
• Progesterone-mediated oocyte maturation
• HTLV-I infection
• Oocyte meiosis