CD05759

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05759

CD05759

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Xpc

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• xeroderma pigmentosum, complementation group C

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• xeroderma pigmentosum, complementation group C
• p125
• xeroderma pigmentosum group C-complementing protein homolog
• DNA repair protein complementing XP-C cells homolog

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/22591

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• xeroderma pigmentosum, complementation group C
  http://metadb.riken.jp/db/mgi_rdf/MGI:103557

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009531

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000030094

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2806

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=613208

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Giuseppina. Giglia-Mari, et.al., Differentiation driven changes in the dynamic organization of Basal transcription initiation., PLoS biology, 2009, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/19841728
• Carmen. Dominguez-Brauer, et.al., ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4., EMBO reports, 2009, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/19644500
• Anastasia. Tsaalbi-Shtylik, et.al., Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/20007784
• A T. Sands, et.al., High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC., Nature, 1995, 377
  http://rdf.ncbi.nlm.nih.gov/pubmed/7675084
• Edoardo. Zattra, et.al., Polypodium leucotomos extract decreases UV-induced Cox-2 expression and inflammation, enhances DNA repair, and decreases mutagenesis in hairless mice., The American journal of pathology, 2009, 175
  http://rdf.ncbi.nlm.nih.gov/pubmed/19808641
• C. Masutani, et.al., Purification and cloning of a nucleotide excision repair complex involving the xeroderma pigmentosum group C protein and a human homologue of yeast RAD23., The EMBO journal, 1994, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/8168482
• L. Li, et.al., Sequence of the mouse XPC cDNA and genomic structure of the human XPC gene., Nucleic acids research, 1996, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/8604333
• R. Legerski, et.al., Expression cloning of a human DNA repair gene involved in xeroderma pigmentosum group C., Nature, 1992, 359
  http://rdf.ncbi.nlm.nih.gov/pubmed/1522891
• H T. Lynch, et.al., Xeroderma pigmentosum. Complementation group C and malignant melanoma., Archives of dermatology, 1984, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/6696469
• Nicole. Verhofstad, et.al., Benzo(a)pyrene induces similar gene expression changes in testis of DNA repair proficient and deficient mice., BMC genomics, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20504355

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• single-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0003697
• nucleotide-excision repair, DNA damage recognition
  http://purl.obolibrary.org/obo/GO_0000715
• response to UV-B
  http://purl.obolibrary.org/obo/GO_0010224
• cell cycle checkpoint
  http://purl.obolibrary.org/obo/GO_0000075
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• XPC complex
  http://purl.obolibrary.org/obo/GO_0071942
• single-stranded DNA binding
  http://purl.obolibrary.org/obo/GO_0006330
• DNA repair
  http://purl.obolibrary.org/obo/GO_0006281
• damaged DNA binding
  http://purl.obolibrary.org/obo/GO_0003684
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• intra-S DNA damage checkpoint
  http://purl.obolibrary.org/obo/GO_0031573
• nucleotide-excision repair
  http://purl.obolibrary.org/obo/GO_0006289
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map03420

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Nucleotide excision repair