CD05927

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05927

CD05927

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Abcg2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• ATP-binding cassette, sub-family G (WHITE), member 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• ATP-binding cassette sub-family G member 2
• breast cancer resistance protein 1 homolog
• ATP-binding cassette, sub-family G (WHITE), member 2
• mitoxantrone resistance protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• MXR
• AI428558
• MXR1
• ABC15
• Bcrp
• Bcrp1
• ABCP
• BCRP

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/26357

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• ATP-binding cassette, sub-family G (WHITE), member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1347061

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011920

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029802

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.333096

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603756

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Yasutomi. Higashikuni, et.al., The ATP-binding cassette transporter BCRP1/ABCG2 plays a pivotal role in cardiac repair after myocardial infarction via modulation of microvascular endothelial cell survival and function., Arteriosclerosis, thrombosis, and vascular biology, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/20829509
• J W. Jonker, et.al., Role of breast cancer resistance protein in the bioavailability and fetal penetration of topotecan., Journal of the National Cancer Institute, 2000, 92
  http://rdf.ncbi.nlm.nih.gov/pubmed/11036110
• Miyuki. Kubota, et.al., The anti-oxidative role of ABCG2 in corneal epithelial cells., Investigative ophthalmology & visual science, 2010, 51
  http://rdf.ncbi.nlm.nih.gov/pubmed/20538997
• J D. Allen, et.al., The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin., Cancer research, 1999, 59
  http://rdf.ncbi.nlm.nih.gov/pubmed/10485464
• D H. Geschwind, et.al., A genetic analysis of neural progenitor differentiation., Neuron, 2001, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/11239426
• Joseph. Tam, et.al., Peripheral CB1 cannabinoid receptor blockade improves cardiometabolic risk in mouse models of obesity., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20664173
• Junichi. Shigeta, et.al., BCRP/ABCG2 confers anticancer drug resistance without covalent dimerization., Cancer science, 2010, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/20518788
• R. Allikmets, et.al., A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance., Cancer research, 1998, 58
  http://rdf.ncbi.nlm.nih.gov/pubmed/9850061
• L M. Schriml, et.al., Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus., Genomics, 2000, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/10708515
• Shanshan. Shen, et.al., ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease., Journal of neurochemistry, 2010, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/20626554

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• apical plasma membrane
  http://purl.obolibrary.org/obo/GO_0016324
• drug transmembrane transporter activity
  http://purl.obolibrary.org/obo/GO_0015238
• drug export
  http://purl.obolibrary.org/obo/GO_0046618
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• protein homodimerization activity
  http://purl.obolibrary.org/obo/GO_0042803
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• nucleoside-triphosphatase activity
  http://purl.obolibrary.org/obo/GO_0017111
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• embryonic process involved in female pregnancy
  http://purl.obolibrary.org/obo/GO_0060136
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• ATPase activity
  http://purl.obolibrary.org/obo/GO_0016887
• drug transmembrane transport
  http://purl.obolibrary.org/obo/GO_0006855
• protein dimerization activity
  http://purl.obolibrary.org/obo/GO_0046983
• urate metabolic process
  http://purl.obolibrary.org/obo/GO_0046415
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• drug transport
  http://purl.obolibrary.org/obo/GO_0015893

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map02010
• http://www.genome.jp/dbget-bin/www_bget?map04976

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• ABC transporters
• Bile secretion