CD06434

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06434

CD06434

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pxn

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• paxillin

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• paxillin

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Pax
• AW123232
• AW108311

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/19303

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• paxillin
  http://metadb.riken.jp/db/mgi_rdf/MGI:108295

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011223
• https://www.ncbi.nlm.nih.gov/nuccore/NM_133915

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000029528

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.18714

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=602505

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Tomohiro. Torii, et.al., Cytohesin-2/ARNO, through its interaction with focal adhesion adaptor protein paxillin, regulates preadipocyte migration via the downstream activation of Arf6., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20525696
• K. Araki, et.al., Exchangeable gene trap using the Cre/mutated lox system., Cellular and molecular biology (Noisy-le-Grand, France), 1999, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/10512203
• Josephine M. Enciso, et.al., Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo., Developmental dynamics : an official publication of the American Association of Anatomists, 2010, 239
  http://rdf.ncbi.nlm.nih.gov/pubmed/20737513
• M M. Kessels, et.al., Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation., Molecular biology of the cell, 2000, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/10637315
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• K M. Lai, et.al., The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10809671
• Pakorn. Kanchanawong, et.al., Nanoscale architecture of integrin-based cell adhesions., Nature, 2010, 468
  http://rdf.ncbi.nlm.nih.gov/pubmed/21107430
• Michelle Y. Abshire, et.al., Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events., Journal of leukocyte biology, 2011, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/21084629
• A E. Engqvist-Goldstein, et.al., An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles., The Journal of cell biology, 1999, 147
  http://rdf.ncbi.nlm.nih.gov/pubmed/10613908
• Y. Mazaki, et.al., Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression., The Journal of biological chemistry, 1998, 273
  http://rdf.ncbi.nlm.nih.gov/pubmed/9712867

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• lamellipodium assembly
  http://purl.obolibrary.org/obo/GO_0030032
• lamellipodium
  http://purl.obolibrary.org/obo/GO_0030027
• peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0018108
• focal adhesion assembly
  http://purl.obolibrary.org/obo/GO_0048041
• cell junction
  http://purl.obolibrary.org/obo/GO_0030054
• macromolecular complex binding
  http://purl.obolibrary.org/obo/GO_0044877
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• beta-catenin binding
  http://purl.obolibrary.org/obo/GO_0008013
• vinculin binding
  http://purl.obolibrary.org/obo/GO_0017166
• focal adhesion
  http://purl.obolibrary.org/obo/GO_0005925
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• zinc ion binding
  http://purl.obolibrary.org/obo/GO_0008270
• cell leading edge
  http://purl.obolibrary.org/obo/GO_0031252
• cell-matrix adhesion
  http://purl.obolibrary.org/obo/GO_0007160
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• integrin binding
  http://purl.obolibrary.org/obo/GO_0005178
• integrin-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0007229
• receptor signaling complex scaffold activity
  http://purl.obolibrary.org/obo/GO_0030159
• cell adhesion
  http://purl.obolibrary.org/obo/GO_0007155
• protein kinase binding
  http://purl.obolibrary.org/obo/GO_0019901
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• movement of cell or subcellular component
  http://purl.obolibrary.org/obo/GO_0006928
• cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0007010
• BH4 domain binding
  http://purl.obolibrary.org/obo/GO_0051435
• growth hormone receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0060396

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04062
• http://www.genome.jp/dbget-bin/www_bget?map04810
• http://www.genome.jp/dbget-bin/www_bget?map05100
• http://www.genome.jp/dbget-bin/www_bget?map04370
• http://www.genome.jp/dbget-bin/www_bget?map04510
• http://www.genome.jp/dbget-bin/www_bget?map04670

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Regulation of actin cytoskeleton
• Bacterial invasion of epithelial cells
• Focal adhesion
• Leukocyte transendothelial migration
• VEGF signaling pathway
• Chemokine signaling pathway