CD06943

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD06943

CD06943

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Cd74

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• HLA-DR-GAMMA
• H-2 class II histocompatibility antigen gamma chain
• ia antigen-associated invariant chain
• histocompatibility: class II antigens, gamma chain of
• class II-associated invariant chain peptide
• Ia-associated invariant chain
• dinucleotide microsatellite
• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
• invariant polypeptide of major histocompatibility complex, class II antigen-associated
• MHC class II-associated invariant chain

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Ia-GAMMA
• CLIP
• HLADG
• DHLAG
• Ii

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16149

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96534

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001042605
• https://www.ncbi.nlm.nih.gov/nuccore/NM_010545

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000024610

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.439737

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=142790

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Nitsan. Maharshak, et.al., CD74 is a survival receptor on colon epithelial cells., World journal of gastroenterology, 2010, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/20614481
• L. Byrd, et.al., Chronic multifocal osteomyelitis, a new recessive mutation on chromosome 18 of the mouse., Genomics, 1991, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/1686018
• Maya. Gordin, et.al., c-Met and its ligand hepatocyte growth factor/scatter factor regulate mature B cell survival in a pathway induced by CD74., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20639480
• Boon Heng Dennis. Teo, et.al., MHC class II-associated invariant chain (Ii) modulates dendritic cells-derived microvesicles (DCMV)-mediated activation of microglia., Biochemical and biophysical research communications, 2010, 400
  http://rdf.ncbi.nlm.nih.gov/pubmed/20816669
• M J. Justice, et.al., A molecular genetic linkage map of mouse chromosome 18 reveals extensive linkage conservation with human chromosomes 5 and 18., Genomics, 1992, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/1354644
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• A M. Wegener, et.al., The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules., Cell, 1992, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/1531041
• D P. Kolk, et.al., The HXY box regulatory element modulates expression of the murine IA antigen-associated invariant chain in L fibroblasts., DNA and cell biology, 1992, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/1457043
• Cornelia H. Rinderknecht, et.al., I-Ag7 is subject to post-translational chaperoning by CLIP., International immunology, 2010, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/20547545
• B A. Mock, et.al., The gene for lysyl oxidase maps to mouse chromosome 18., Genomics, 1992, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/1358813

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• NOS2-CD74 complex
  http://purl.obolibrary.org/obo/GO_0035693
• negative regulation of peptide secretion
  http://purl.obolibrary.org/obo/GO_0002792
• macrophage migration inhibitory factor receptor complex
  http://purl.obolibrary.org/obo/GO_0035692
• positive regulation of T cell differentiation
  http://purl.obolibrary.org/obo/GO_0045582
• receptor complex
  http://purl.obolibrary.org/obo/GO_0043235
• negative regulation of T cell differentiation
  http://purl.obolibrary.org/obo/GO_0045581
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• negative regulation of DNA damage response, signal transduction by p53 class mediator
  http://purl.obolibrary.org/obo/GO_0043518
• multivesicular body
  http://purl.obolibrary.org/obo/GO_0005771
• late endosome
  http://purl.obolibrary.org/obo/GO_0005770
• positive regulation of fibroblast proliferation
  http://purl.obolibrary.org/obo/GO_0048146
• positive regulation of innate immune response
  http://purl.obolibrary.org/obo/GO_0045089
• positive regulation of type 2 immune response
  http://purl.obolibrary.org/obo/GO_0002830
• cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0019221
• positive regulation of macrophage cytokine production
  http://purl.obolibrary.org/obo/GO_0060907
• intracellular protein transport
  http://purl.obolibrary.org/obo/GO_0006886
• beta-amyloid binding
  http://purl.obolibrary.org/obo/GO_0001540
• antigen processing and presentation
  http://purl.obolibrary.org/obo/GO_0019882
• immunoglobulin mediated immune response
  http://purl.obolibrary.org/obo/GO_0016064
• prostaglandin biosynthetic process
  http://purl.obolibrary.org/obo/GO_0001516
• negative regulation of mature B cell apoptotic process
  http://purl.obolibrary.org/obo/GO_0002906
• macromolecular complex assembly
  http://purl.obolibrary.org/obo/GO_0065003
• nitric-oxide synthase binding
  http://purl.obolibrary.org/obo/GO_0050998
• cell proliferation
  http://purl.obolibrary.org/obo/GO_0008283
• vacuole
  http://purl.obolibrary.org/obo/GO_0005773
• positive thymic T cell selection
  http://purl.obolibrary.org/obo/GO_0045059
• positive regulation of cytokine-mediated signaling pathway
  http://purl.obolibrary.org/obo/GO_0001961
• positive regulation of chemokine (C-X-C motif) ligand 2 production
  http://purl.obolibrary.org/obo/GO_2000343
• cytokine receptor activity
  http://purl.obolibrary.org/obo/GO_0004896
• immune response
  http://purl.obolibrary.org/obo/GO_0006955
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cytokine binding
  http://purl.obolibrary.org/obo/GO_0019955
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• positive regulation of adaptive immune response
  http://purl.obolibrary.org/obo/GO_0002821
• negative thymic T cell selection
  http://purl.obolibrary.org/obo/GO_0045060
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783
• macrophage migration inhibitory factor signaling pathway
  http://purl.obolibrary.org/obo/GO_0035691
• positive regulation of B cell proliferation
  http://purl.obolibrary.org/obo/GO_0030890
• chaperone mediated protein folding requiring cofactor
  http://purl.obolibrary.org/obo/GO_0051085
• positive regulation of peptidyl-tyrosine phosphorylation
  http://purl.obolibrary.org/obo/GO_0050731
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• positive regulation of dendritic cell antigen processing and presentation
  http://purl.obolibrary.org/obo/GO_0002606
• external side of plasma membrane
  http://purl.obolibrary.org/obo/GO_0009897
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• positive regulation of neutrophil chemotaxis
  http://purl.obolibrary.org/obo/GO_0090023
• MHC class II protein complex
  http://purl.obolibrary.org/obo/GO_0042613
• positive regulation of ERK1 and ERK2 cascade
  http://purl.obolibrary.org/obo/GO_0070374
• MHC class II protein binding
  http://purl.obolibrary.org/obo/GO_0042289
• lysosome
  http://purl.obolibrary.org/obo/GO_0005764
• antigen processing and presentation of exogenous peptide antigen via MHC class II
  http://purl.obolibrary.org/obo/GO_0019886
• integral component of plasma membrane
  http://purl.obolibrary.org/obo/GO_0005887
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• defense response
  http://purl.obolibrary.org/obo/GO_0006952
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04612
• http://www.genome.jp/dbget-bin/www_bget?map05168
• http://www.genome.jp/dbget-bin/www_bget?map05152

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Herpes simplex infection
• Tuberculosis
• Antigen processing and presentation