CD07081

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07081

CD07081

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Nfatc2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• nuclear factor of activated T-cells, cytoplasmic 2
• nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
• NF-ATp
• T-cell transcription factor NFAT1
• NFAT pre-existing subunit

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Nfatp
• NF-ATc2
• NFATp
• NFAT1-D
• AI607462
• NFAT1

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18019

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102463

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001037178
• https://www.ncbi.nlm.nih.gov/nuccore/NM_010899
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001037177
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001136073

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027544

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.116802

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=600490

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Kubo, et.al., Activation of the interleukin-4 gene is controlled by the unique calcineurin-dependent transcriptional factor NF(P)., The Journal of biological chemistry, 1994, 269
  http://rdf.ncbi.nlm.nih.gov/pubmed/8034712
• Woon-Ki. Kim, et.al., Nuclear factor of activated T cells negatively regulates expression of the tumor necrosis factor receptor-related 2 gene in T cells., Experimental & molecular medicine, 2010, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/20948279
• Yoshiharu. Ohoka, et.al., Retinoic acid-induced CCR9 expression requires transient TCR stimulation and cooperativity between NFATc2 and the retinoic acid receptor/retinoid X receptor complex., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
  http://rdf.ncbi.nlm.nih.gov/pubmed/21148038
• P G. McCaffrey, et.al., Isolation of the cyclosporin-sensitive T cell transcription factor NFATp., Science (New York, N.Y.), 1993, 262
  http://rdf.ncbi.nlm.nih.gov/pubmed/8235597
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• X. Li, et.al., Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp., Cytogenetics and cell genetics, 1995, 68
  http://rdf.ncbi.nlm.nih.gov/pubmed/7842733
• J. Jain, et.al., A similar DNA-binding motif in NFAT family proteins and the Rel homology region., The Journal of biological chemistry, 1995, 270
  http://rdf.ncbi.nlm.nih.gov/pubmed/7876165
• A M. Ho, et.al., Expression of the transcription factor NFATp in a neuronal cell line and in the murine nervous system., The Journal of biological chemistry, 1994, 269
  http://rdf.ncbi.nlm.nih.gov/pubmed/7961754
• Naoki. Hayashida, et.al., Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20834230
• Srimoyee. Ghosh, et.al., Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis., Proceedings of the National Academy of Sciences of the United States of America, 2010, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/20696888

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• positive regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010628
• cellular response to DNA damage stimulus
  http://purl.obolibrary.org/obo/GO_0006974
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• cytokine production
  http://purl.obolibrary.org/obo/GO_0001816
• B cell receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0050853
• actin cytoskeleton
  http://purl.obolibrary.org/obo/GO_0015629
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• response to drug
  http://purl.obolibrary.org/obo/GO_0042493
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• positive regulation of B cell proliferation
  http://purl.obolibrary.org/obo/GO_0030890
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04370
• http://www.genome.jp/dbget-bin/www_bget?map04660
• http://www.genome.jp/dbget-bin/www_bget?map04310
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04662
• http://www.genome.jp/dbget-bin/www_bget?map04360
• http://www.genome.jp/dbget-bin/www_bget?map04650
• http://www.genome.jp/dbget-bin/www_bget?map04010

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• T cell receptor signaling pathway
• B cell receptor signaling pathway
• VEGF signaling pathway
• Natural killer cell mediated cytotoxicity
• Wnt signaling pathway
• HTLV-I infection
• MAPK signaling pathway
• Axon guidance