CD07187

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD07187

CD07187

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Setd8

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• SET domain containing (lysine methyltransferase) 8

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• PR/SET domain-containing protein 07
• N-lysine methyltransferase SETD8
• H4-K20-HMTase SETD8
• SET domain-containing protein 8
• PR/SET07
• histone-lysine N-methyltransferase SETD8
• SET domain containing (lysine methyltransferase) 8

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2410195B05Rik
• AW536475
• AA617402
• PR-SET7

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/67956

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• lysine methyltransferase 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1915206

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_030241

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000049327

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.137966

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=607240

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K. Araki, et.al., Exchangeable gene trap using the Cre/mutated lox system., Cellular and molecular biology (Noisy-le-Grand, France), 1999, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/10512203
• Loydie A. Jerome-Majewska, et.al., The trafficking protein Tmed2/p24beta(1) is required for morphogenesis of the mouse embryo and placenta., Developmental biology, 2010, 341
  http://rdf.ncbi.nlm.nih.gov/pubmed/20178780
• Maëlle. Pannetier, et.al., PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse., EMBO reports, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18724273
• Bing. Xiao, et.al., SET domains and histone methylation., Current opinion in structural biology, 2003, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/14675547
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Takuya. Taniwaki, et.al., Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette., Development, growth & differentiation, 2005, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/15840001
• Jia. Fang, et.al., Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase., Current biology : CB, 2002, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/12121615
• Zhenfei. Li, et.al., Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21282610
• Ken-ichi. Wakabayashi, et.al., The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19414603
• Hisanobu. Oda, et.al., Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development., Molecular and cellular biology, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19223465

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• covalent chromatin modification
  http://purl.obolibrary.org/obo/GO_0016569
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355
• mitotic cell cycle
  http://purl.obolibrary.org/obo/GO_0000278
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• chromosome
  http://purl.obolibrary.org/obo/GO_0005694
• protein-lysine N-methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0016279
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• p53 binding
  http://purl.obolibrary.org/obo/GO_0002039
• chromatin organization
  http://purl.obolibrary.org/obo/GO_0006325
• peptidyl-lysine monomethylation
  http://purl.obolibrary.org/obo/GO_0018026
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• transcription corepressor activity
  http://purl.obolibrary.org/obo/GO_0003714
• regulation of DNA damage response, signal transduction by p53 class mediator
  http://purl.obolibrary.org/obo/GO_0043516
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• cell division
  http://purl.obolibrary.org/obo/GO_0051301
• methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0008168
• histone lysine methylation
  http://purl.obolibrary.org/obo/GO_0034968
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• histone-lysine N-methyltransferase activity
  http://purl.obolibrary.org/obo/GO_0018024
• methylation
  http://purl.obolibrary.org/obo/GO_0032259

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00310

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Lysine degradation