Brain Transcriptome Database (BrainTx)
トランスクリプトームデータ
CD08688
http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD08688
CD08688(トランスクリプトームデータ)
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CD08688
トランスクリプトームデータ
遺伝子シンボル
http://metadb.riken.jp/db/BrainTx/geneSymbol
Apoe
遺伝子名
http://metadb.riken.jp/db/BrainTx/geneName
apolipoprotein E
別名
http://metadb.riken.jp/db/BrainTx/alt_name
apo-E
apolipoprotein E
別名略称
http://metadb.riken.jp/db/BrainTx/alt_symbol
AI255918
NCBI遺伝子
http://metadb.riken.jp/db/BrainTx/NCBIGene
https://www.ncbi.nlm.nih.gov/gene/11816
MGI遺伝子
http://metadb.riken.jp/db/BrainTx/mgiGene
apolipoprotein E
http://metadb.riken.jp/db/mgi_rdf/MGI:88057
BrainTx遺伝子
http://metadb.riken.jp/db/BrainTx/brainTxGene
脳発現画像
http://metadb.riken.jp/db/BrainTx/brainExpressionImage
時系列発現 (小脳)
http://metadb.riken.jp/db/BrainTx/brainExpression
脳発現特異性/組織別発現
http://metadb.riken.jp/db/BrainTx/brainSpecificity
BrainTx遺伝子カテゴリー
http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory
NCBI Accession Number
http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber
https://www.ncbi.nlm.nih.gov/nuccore/NM_009696
Ensembl 遺伝子
http://metadb.riken.jp/db/BrainTx/ensemblGene
http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000002985
UniGene 遺伝子
http://metadb.riken.jp/db/BrainTx/uniGene
https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.305152
OMIM ID
http://metadb.riken.jp/db/BrainTx/omim
https://www.omim.org/entry/603434?search=603434&highlight=107741
PubMed ID (PMID)
http://rdf.ncbi.nlm.nih.gov/pubmed/
Yehuda. Kamari, et.al., Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α., Biochemical and biophysical research communications, 2011, 405
http://rdf.ncbi.nlm.nih.gov/pubmed/21219852
F. Rudert, et.al., Characterization of murine carcinoembryonic antigen gene family members., Mammalian genome : official journal of the International Mammalian Genome Society, 1992, 3
http://rdf.ncbi.nlm.nih.gov/pubmed/1638085
J A. Piedrahita, et.al., Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells., Proceedings of the National Academy of Sciences of the United States of America, 1992, 89
http://rdf.ncbi.nlm.nih.gov/pubmed/1584779
Shaw-Yung. Shai, et.al., Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice., American journal of physiology. Heart and circulatory physiology, 2011, 300
http://rdf.ncbi.nlm.nih.gov/pubmed/21335474
Tae Whan. Kim, et.al., The critical role of IL-1 receptor-associated kinase 4-mediated NF-κB activation in modified low-density lipoprotein-induced inflammatory gene expression and atherosclerosis., Journal of immunology (Baltimore, Md. : 1950), 2011, 186
http://rdf.ncbi.nlm.nih.gov/pubmed/21278342
Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
S H. Zhang, et.al., Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E., Science (New York, N.Y.), 1992, 258
http://rdf.ncbi.nlm.nih.gov/pubmed/1411543
Barend. Mees, et.al., Endothelial nitric oxide synthase overexpression restores the efficiency of bone marrow mononuclear cell-based therapy., The American journal of pathology, 2011, 178
http://rdf.ncbi.nlm.nih.gov/pubmed/21224043
A S. Plump, et.al., Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells., Cell, 1992, 71
http://rdf.ncbi.nlm.nih.gov/pubmed/1423598
N. Agarwal, et.al., Sequence analysis, expression and chromosomal localization of a gene, isolated from a subtracted human retina cDNA library, that encodes an insulin-like growth factor binding protein (IGFBP2)., Experimental eye research, 1991, 52
http://rdf.ncbi.nlm.nih.gov/pubmed/1712312
Gene Ontology
http://metadb.riken.jp/db/BrainTx/golink
nitric oxide mediated signal transduction
http://purl.obolibrary.org/obo/GO_0007263
negative regulation of apoptotic process
http://purl.obolibrary.org/obo/GO_0043066
metal chelating activity
http://purl.obolibrary.org/obo/GO_0046911
very-low-density lipoprotein particle remodeling
http://purl.obolibrary.org/obo/GO_0034372
artery morphogenesis
http://purl.obolibrary.org/obo/GO_0048844
negative regulation of endothelial cell proliferation
http://purl.obolibrary.org/obo/GO_0001937
cytoplasm
http://purl.obolibrary.org/obo/GO_0005737
positive regulation of nitric-oxide synthase activity
http://purl.obolibrary.org/obo/GO_0051000
lipoprotein metabolic process
http://purl.obolibrary.org/obo/GO_0042157
cholesterol metabolic process
http://purl.obolibrary.org/obo/GO_0008203
response to dietary excess
http://purl.obolibrary.org/obo/GO_0002021
late endosome
http://purl.obolibrary.org/obo/GO_0005770
positive regulation of cholesterol efflux
http://purl.obolibrary.org/obo/GO_0010875
extracellular space
http://purl.obolibrary.org/obo/GO_0005615
cellular calcium ion homeostasis
http://purl.obolibrary.org/obo/GO_0006874
low-density lipoprotein particle remodeling
http://purl.obolibrary.org/obo/GO_0034374
receptor-mediated endocytosis
http://purl.obolibrary.org/obo/GO_0006898
Cdc42 protein signal transduction
http://purl.obolibrary.org/obo/GO_0032488
very-low-density lipoprotein particle receptor binding
http://purl.obolibrary.org/obo/GO_0070326
low-density lipoprotein particle
http://purl.obolibrary.org/obo/GO_0034362
extrinsic component of external side of plasma membrane
http://purl.obolibrary.org/obo/GO_0031232
apoptotic process
http://purl.obolibrary.org/obo/GO_0006915
lipoprotein catabolic process
http://purl.obolibrary.org/obo/GO_0042159
positive regulation of low-density lipoprotein particle receptor catabolic process
http://purl.obolibrary.org/obo/GO_0032805
reverse cholesterol transport
http://purl.obolibrary.org/obo/GO_0043691
lipid metabolic process
http://purl.obolibrary.org/obo/GO_0006629
negative regulation of platelet activation
http://purl.obolibrary.org/obo/GO_0010544
neuronal cell body
http://purl.obolibrary.org/obo/GO_0043025
extracellular region
http://purl.obolibrary.org/obo/GO_0005576
cholesterol homeostasis
http://purl.obolibrary.org/obo/GO_0042632
cholesterol transporter activity
http://purl.obolibrary.org/obo/GO_0017127
phospholipid binding
http://purl.obolibrary.org/obo/GO_0005543
response to oxidative stress
http://purl.obolibrary.org/obo/GO_0006979
chylomicron remnant clearance
http://purl.obolibrary.org/obo/GO_0034382
positive regulation of cGMP biosynthetic process
http://purl.obolibrary.org/obo/GO_0030828
negative regulation of blood coagulation
http://purl.obolibrary.org/obo/GO_0030195
lipid transporter activity
http://purl.obolibrary.org/obo/GO_0005319
lipid transport
http://purl.obolibrary.org/obo/GO_0006869
dendrite
http://purl.obolibrary.org/obo/GO_0030425
phospholipid efflux
http://purl.obolibrary.org/obo/GO_0033700
protein localization
http://purl.obolibrary.org/obo/GO_0008104
aging
http://purl.obolibrary.org/obo/GO_0007568
lipoprotein particle binding
http://purl.obolibrary.org/obo/GO_0071813
cholesterol catabolic process
http://purl.obolibrary.org/obo/GO_0006707
regulation of gene expression
http://purl.obolibrary.org/obo/GO_0010468
chylomicron
http://purl.obolibrary.org/obo/GO_0042627
cGMP-mediated signaling
http://purl.obolibrary.org/obo/GO_0019934
negative regulation of cholesterol biosynthetic process
http://purl.obolibrary.org/obo/GO_0045541
maintenance of location in cell
http://purl.obolibrary.org/obo/GO_0051651
axon regeneration
http://purl.obolibrary.org/obo/GO_0031103
protein homodimerization activity
http://purl.obolibrary.org/obo/GO_0042803
high-density lipoprotein particle
http://purl.obolibrary.org/obo/GO_0034364
low-density lipoprotein particle receptor binding
http://purl.obolibrary.org/obo/GO_0050750
response to ethanol
http://purl.obolibrary.org/obo/GO_0045471
lipid binding
http://purl.obolibrary.org/obo/GO_0006630
cholesterol efflux
http://purl.obolibrary.org/obo/GO_0033344
phosphatidylcholine-sterol O-acyltransferase activator activity
http://purl.obolibrary.org/obo/GO_0060228
antioxidant activity
http://purl.obolibrary.org/obo/GO_0016209
lipid binding
http://purl.obolibrary.org/obo/GO_0008289
transport
http://purl.obolibrary.org/obo/GO_0006810
beta-amyloid binding
http://purl.obolibrary.org/obo/GO_0001540
very-low-density lipoprotein particle
http://purl.obolibrary.org/obo/GO_0034361
heparin binding
http://purl.obolibrary.org/obo/GO_0008201
cardiovascular system development
http://purl.obolibrary.org/obo/GO_0072358
vasodilation
http://purl.obolibrary.org/obo/GO_0042311
triglyceride metabolic process
http://purl.obolibrary.org/obo/GO_0006641
positive regulation of cholesterol esterification
http://purl.obolibrary.org/obo/GO_0010873
high-density lipoprotein particle assembly
http://purl.obolibrary.org/obo/GO_0034380
very-low-density lipoprotein particle clearance
http://purl.obolibrary.org/obo/GO_0034447
lipoprotein biosynthetic process
http://purl.obolibrary.org/obo/GO_0042158
negative regulation of MAP kinase activity
http://purl.obolibrary.org/obo/GO_0043407
high-density lipoprotein particle clearance
http://purl.obolibrary.org/obo/GO_0034384
lipid homeostasis
http://purl.obolibrary.org/obo/GO_0055088
early endosome
http://purl.obolibrary.org/obo/GO_0005769
tau protein binding
http://purl.obolibrary.org/obo/GO_0048156
positive regulation of membrane protein ectodomain proteolysis
http://purl.obolibrary.org/obo/GO_0051044
microtubule
http://purl.obolibrary.org/obo/GO_0005874
high-density lipoprotein particle remodeling
http://purl.obolibrary.org/obo/GO_0034375
negative regulation of blood vessel endothelial cell migration
http://purl.obolibrary.org/obo/GO_0043537
protein heterodimerization activity
http://purl.obolibrary.org/obo/GO_0046982
identical protein binding
http://purl.obolibrary.org/obo/GO_0042802
G-protein coupled receptor signaling pathway
http://purl.obolibrary.org/obo/GO_0007186
Golgi apparatus
http://purl.obolibrary.org/obo/GO_0005794
intermediate-density lipoprotein particle
http://purl.obolibrary.org/obo/GO_0034363
InterPro ID
http://metadb.riken.jp/db/BrainTx/interPro
KEGG Pathway ID
http://metadb.riken.jp/db/BrainTx/keggPathwayID
http://www.genome.jp/dbget-bin/www_bget?map05010
KEGG Pathway 名称
http://metadb.riken.jp/db/BrainTx/keggPathwayName
Alzheimer's disease
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