CD09101

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD09101

CD09101

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rasgrp1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• RAS guanyl releasing protein 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• calcium and DAG-regulated guanine nucleotide exchange factor II
• RAS guanyl releasing protein 1
• calDAG-GEFII
• RAS guanyl-releasing protein 1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Rasgrp

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/19419

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• RAS guanyl releasing protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314635

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011246

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000027347

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.42150

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603962

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Benjamin. Ko, et.al., RasGRP1 stimulation enhances ubiquitination and endocytosis of the sodium-chloride cotransporter., American journal of physiology. Renal physiology, 2010, 299
  http://rdf.ncbi.nlm.nih.gov/pubmed/20392800
• J. Li, et.al., Leukaemia disease genes: large-scale cloning and pathway predictions., Nature genetics, 1999, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/10610183
• John J. Priatel, et.al., RasGRP1 regulates antigen-induced developmental programming by naive CD8 T cells., Journal of immunology (Baltimore, Md. : 1950), 2010, 184
  http://rdf.ncbi.nlm.nih.gov/pubmed/20007535
• N A. Dower, et.al., RasGRP is essential for mouse thymocyte differentiation and TCR signaling., Nature immunology, 2000, 1
  http://rdf.ncbi.nlm.nih.gov/pubmed/11017103
• Amrish. Sharma, et.al., RasGRP1 is essential for ras activation by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate in epidermal keratinocytes., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20308057
• Suk Hyung. Lee, et.al., RasGRP1 is required for human NK cell function., Journal of immunology (Baltimore, Md. : 1950), 2009, 183
  http://rdf.ncbi.nlm.nih.gov/pubmed/19933860
• John J. Priatel, et.al., RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation., Immunity, 2002, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12433368
• Anne M. Norment, et.al., Transgenic expression of RasGRP1 induces the maturation of double-negative thymocytes and enhances the production of CD8 single-positive thymocytes., Journal of immunology (Baltimore, Md. : 1950), 2003, 170
  http://rdf.ncbi.nlm.nih.gov/pubmed/12538669
• D. Bottorff, et.al., RasGRP, a Ras activator: mouse and human cDNA sequences and chromosomal positions., Mammalian genome : official journal of the International Mammalian Genome Society, 1999, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/10087292
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• calcium ion binding
  http://purl.obolibrary.org/obo/GO_0005509
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• guanyl-nucleotide exchange factor activity
  http://purl.obolibrary.org/obo/GO_0005085
• intracellular
  http://purl.obolibrary.org/obo/GO_0005622
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• intracellular signal transduction
  http://purl.obolibrary.org/obo/GO_0035556
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell differentiation
  http://purl.obolibrary.org/obo/GO_0030154
• regulation of catalytic activity
  http://purl.obolibrary.org/obo/GO_0050790
• regulation of small GTPase mediated signal transduction
  http://purl.obolibrary.org/obo/GO_0051056
• small GTPase mediated signal transduction
  http://purl.obolibrary.org/obo/GO_0007264
• endoplasmic reticulum
  http://purl.obolibrary.org/obo/GO_0005783

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04010
• http://www.genome.jp/dbget-bin/www_bget?map04660

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• MAPK signaling pathway
• T cell receptor signaling pathway