CD10443

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10443

CD10443

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Ppp2r2a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• PP2A subunit B isoform alpha
• PP2A subunit B isoform R2-alpha
• PP2A subunit B isoform PR55-alpha
• serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
• protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
• PP2A subunit B isoform B55-alpha

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• 2410004D02Rik
• mKIAA1541

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/71978

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• protein phosphatase 2, regulatory subunit B, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919228

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_028032
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001205188

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022052

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.273997

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=604941

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Gilda. Cobellis, et.al., Tagging genes with cassette-exchange sites., Nucleic acids research, 2005, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/15741177
• Noriko. Okazaki, et.al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries., DNA research : an international journal for rapid publication of reports on genes and genomes, 2003, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/14621295
• Doug. Stryke, et.al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells., Nucleic acids research, 2003, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/12520002
• Takehiko. Maeda, et.al., Morphine has an antinociceptive effect through activation of the okadaic-acid-sensitive Ser/Thr protein phosphatases PP 2 A and PP5 estimated by tail-pinch test in mice., Brain research, 2005, 1056
  http://rdf.ncbi.nlm.nih.gov/pubmed/16102737
• Wen-Bin. Liu, et.al., Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye., Molecular vision, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18432318
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Ryan F L. O'Shaughnessy, et.al., Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development., Development (Cambridge, England), 2009, 136
  http://rdf.ncbi.nlm.nih.gov/pubmed/19762425
• Yi-Chun. Kuo, et.al., Regulation of phosphorylation of Thr-308 of Akt, cell proliferation, and survival by the B55alpha regulatory subunit targeting of the protein phosphatase 2A holoenzyme to Akt., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18042541
• Susan. Magdaleno, et.al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system., PLoS biology, 2006, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/16602821

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• protein dephosphorylation
  http://purl.obolibrary.org/obo/GO_0006470
• protein phosphatase type 2A complex
  http://purl.obolibrary.org/obo/GO_0000159
• regulation of catalytic activity
  http://purl.obolibrary.org/obo/GO_0050790
• protein phosphatase regulator activity
  http://purl.obolibrary.org/obo/GO_0019888
• protein serine/threonine phosphatase activity
  http://purl.obolibrary.org/obo/GO_0004722
• response to morphine
  http://purl.obolibrary.org/obo/GO_0043278

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04530
• http://www.genome.jp/dbget-bin/www_bget?map04728
• http://www.genome.jp/dbget-bin/www_bget?map05142
• http://www.genome.jp/dbget-bin/www_bget?map03015
• http://www.genome.jp/dbget-bin/www_bget?map05160

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Dopaminergic synapse
• Hepatitis C
• Chagas disease (American trypanosomiasis)
• Tight junction
• mRNA surveillance pathway