CD10688

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10688

CD10688

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Smpd3

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• sphingomyelin phosphodiesterase 3, neutral

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• neutral sphingomyelinase 2
• sphingomyelin phosphodiesterase 3, neutral
• sphingomyelin phosphodiesterase 3
• nSMase-2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AW537966
• 4631433G07Rik
• fro
• neutral sphingomyelinase II
• nSMase2
• AI427456

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/58994

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• sphingomyelin phosphodiesterase 3, neutral
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927578

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_021491

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000031906

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.23298

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=605777

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K S. Brown, et.al., Craniofacial consequences of connective tissue disorders in mice., Birth defects original article series, 1984, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/6391574
• M P. Muriel, et.al., Morphological and biochemical studies of a mouse mutant (fro/fro) with bone fragility., Bone, 1991, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1793673
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Raphael. Devillard, et.al., Stress-induced sphingolipid signaling: role of type-2 neutral sphingomyelinase in murine cell apoptosis and proliferation., PloS one, 2010, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/20352118
• Olga. Golonzhka, et.al., Dual role of COUP-TF-interacting protein 2 in epidermal homeostasis and permeability barrier formation., The Journal of investigative dermatology, 2009, 129
  http://rdf.ncbi.nlm.nih.gov/pubmed/19092943
• D O. Sillence, et.al., Fragilitas ossium (fro/fro) in the mouse: a model for a recessively inherited type of osteogenesis imperfecta., American journal of medical genetics, 1993, 45
  http://rdf.ncbi.nlm.nih.gov/pubmed/8456819
• K. Hofmann, et.al., Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/10823942
• http://rdf.ncbi.nlm.nih.gov/pubmed/6801109
• Nino. Tabatadze, et.al., Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice., Journal of neuroscience research, 2010, 88
  http://rdf.ncbi.nlm.nih.gov/pubmed/20629193
• Young-Mi. Chae, et.al., Upregulation of smpd3 via BMP2 stimulation and Runx2., BMB reports, 2009, 42
  http://rdf.ncbi.nlm.nih.gov/pubmed/19250608

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• response to stress
  http://purl.obolibrary.org/obo/GO_0006950
• Golgi cis cisterna
  http://purl.obolibrary.org/obo/GO_0000137
• peptide hormone secretion
  http://purl.obolibrary.org/obo/GO_0030072
• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• Golgi apparatus
  http://purl.obolibrary.org/obo/GO_0005794
• metal ion binding
  http://purl.obolibrary.org/obo/GO_0046872
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• sphingomyelin metabolic process
  http://purl.obolibrary.org/obo/GO_0006684
• metabolic process
  http://purl.obolibrary.org/obo/GO_0008152
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• hydrolase activity
  http://purl.obolibrary.org/obo/GO_0016787
• sphingomyelin phosphodiesterase activity
  http://purl.obolibrary.org/obo/GO_0004767
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00600
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Sphingolipid metabolism