CD11763

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11763

CD11763

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pdcd6ip

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• programmed cell death 6 interacting protein

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• E2f1-inducible protein
• programmed cell death 6 interacting protein
• ALG-2-interacting protein 1
• programmed cell death 6-interacting protein
• Alg2-interacting protein X
• Alg2-interacting protein 1
• ALG-2-interacting protein X

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Eig2
• Alix
• AI480591
• C76364
• Aip1
• AW544830
• AIP1
• mKIAA1375

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18571

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• programmed cell death 6 interacting protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333753

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011052
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001164678
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001164677

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000032504

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.29816

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=608074

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Laurence. Aubry, et.al., Biochemical characterization of two analogues of the apoptosis-linked gene 2 protein in Dictyostelium discoideum and interaction with a physiological partner in mammals, murine Alix., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/11927596
• Huan-Yuan. Chen, et.al., Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19706535
• B. Chen, et.al., The glioma-associated protein SETA interacts with AIP1/Alix and ALG-2 and modulates apoptosis in astrocytes., The Journal of biological chemistry, 2000, 275
  http://rdf.ncbi.nlm.nih.gov/pubmed/10858458
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Micha. Hoffmann, et.al., Enterococcus faecalis strains differentially regulate Alix/AIP1 protein expression and ERK 1/2 activation in intestinal epithelial cells in the context of chronic experimental colitis., Journal of proteome research, 2009, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/19166300
• Shujuan. Pan, et.al., Extracellular Alix regulates integrin-mediated cell adhesions and extracellular matrix assembly., The EMBO journal, 2008, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/18636094
• Christine. Chatellard-Causse, et.al., Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/12034747
• M. Missotten, et.al., Alix, a novel mouse protein undergoing calcium-dependent interaction with the apoptosis-linked-gene 2 (ALG-2) protein., Cell death and differentiation, 1999, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/10200558
• Flavie. Strappazzon, et.al., Alix is involved in caspase 9 activation during calcium-induced apoptosis., Biochemical and biophysical research communications, 2010, 397
  http://rdf.ncbi.nlm.nih.gov/pubmed/20471954
• P. Vito, et.al., Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction., The Journal of biological chemistry, 1999, 274
  http://rdf.ncbi.nlm.nih.gov/pubmed/9880530

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• calcium-dependent protein binding
  http://purl.obolibrary.org/obo/GO_0048306
• cell division
  http://purl.obolibrary.org/obo/GO_0051301
• apoptotic process
  http://purl.obolibrary.org/obo/GO_0006915
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• cytosol
  http://purl.obolibrary.org/obo/GO_0005829
• cell cycle
  http://purl.obolibrary.org/obo/GO_0007049
• protein transport
  http://purl.obolibrary.org/obo/GO_0015031
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• SH3 domain binding
  http://purl.obolibrary.org/obo/GO_0017124
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• protein dimerization activity
  http://purl.obolibrary.org/obo/GO_0046983

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04144

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Endocytosis