CD11922

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11922

CD11922

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Chkb

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• choline kinase beta

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• choline/ethanolaminekinase
• choline kinase beta
• choline/ethanolamine kinase-b
• ethanolamine kinase
• choline/ethanolamine kinase

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Ck/Ek-beta
• Ek
• Ckekb
• Ck
• CK/EK-beta
• Ckb
• Chetk
• Chkl
• Ck/Ek

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/12651

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• choline kinase beta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328313

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_007692

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000022617

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.485045

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=612395

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Naoshi. Yamazaki, et.al., The gene encoding muscle-type carnitine palmitoyltransferase I: comparison of the 5'-upstream region of human and rodent genes., Journal of biochemistry, 2003, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/12761301
• C. Aoyama, et.al., Molecular cloning of mouse choline kinase and choline/ethanolamine kinase: their sequence comparison to the respective rat homologs., Biochimica et biophysica acta, 1998, 1393
  http://rdf.ncbi.nlm.nih.gov/pubmed/9714798
• Huanan. Liao, et.al., Deletion and alanine mutation analyses for the formation of active homo- or hetero-dimer complexes of mouse choline kinase-alpha and -beta., Biochimica et biophysica acta, 2006, 1761
  http://rdf.ncbi.nlm.nih.gov/pubmed/16490392
• Feike R. van der Leij, et.al., Structural and functional genomics of the CPT1B gene for muscle-type carnitine palmitoyltransferase I in mammals., The Journal of biological chemistry, 2002, 277
  http://rdf.ncbi.nlm.nih.gov/pubmed/12015320
• C. Aoyama, et.al., Structure and characterization of the genes for murine choline/ethanolamine kinase isozymes alpha and beta., Journal of lipid research, 2000, 41
  http://rdf.ncbi.nlm.nih.gov/pubmed/10706593
• Gengshu. Wu, et.al., Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse., Biochimica et biophysica acta, 2010, 1801
  http://rdf.ncbi.nlm.nih.gov/pubmed/20026284
• Chieko. Aoyama, et.al., Expression and characterization of the active molecular forms of choline/ethanolamine kinase-alpha and -beta in mouse tissues, including carbon tetrachloride-induced liver., The Biochemical journal, 2002, 363
  http://rdf.ncbi.nlm.nih.gov/pubmed/11964179
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• Gengshu. Wu, et.al., Understanding the muscular dystrophy caused by deletion of choline kinase beta in mice., Biochimica et biophysica acta, 2009, 1791
  http://rdf.ncbi.nlm.nih.gov/pubmed/19236939
• Roger B. Sher, et.al., A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis., The Journal of biological chemistry, 2006, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/16371353

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• muscle organ development
  http://purl.obolibrary.org/obo/GO_0007517
• ATP binding
  http://purl.obolibrary.org/obo/GO_0005524
• transferase activity
  http://purl.obolibrary.org/obo/GO_0016740
• kinase activity
  http://purl.obolibrary.org/obo/GO_0016301
• phosphotransferase activity, alcohol group as acceptor
  http://purl.obolibrary.org/obo/GO_0016773
• phosphatidylcholine biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006656
• phosphorylation
  http://purl.obolibrary.org/obo/GO_0016310
• nucleotide binding
  http://purl.obolibrary.org/obo/GO_0000166
• phosphatidylethanolamine biosynthetic process
  http://purl.obolibrary.org/obo/GO_0006646
• choline kinase activity
  http://purl.obolibrary.org/obo/GO_0004103
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• phospholipid biosynthetic process
  http://purl.obolibrary.org/obo/GO_0008654
• ethanolamine kinase activity
  http://purl.obolibrary.org/obo/GO_0004305
• transferase activity, transferring phosphorus-containing groups
  http://purl.obolibrary.org/obo/GO_0016772
• CDP-choline pathway
  http://purl.obolibrary.org/obo/GO_0006657

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map00564
• http://www.genome.jp/dbget-bin/www_bget?map01100

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Metabolic pathways
• Glycerophospholipid metabolism