CD12095

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12095

CD12095

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Wnt5a

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• wingless-related MMTV integration site 5A

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• wingless-related MMTV integration site 5A
• protein Wnt-5a

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• Wnt-5a
• 8030457G12Rik

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/22418

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• wingless-type MMTV integration site family, member 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:98958

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_009524

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000021994

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.287544

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=164975

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• B J. Gavin, et.al., Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development., Genes & development, 1990, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/2279700
• A P. McMahon, et.al., The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum., Cell, 1992, 69
  http://rdf.ncbi.nlm.nih.gov/pubmed/1534034
• R. Nusse, et.al., A new nomenclature for int-1 and related genes: the Wnt gene family., Cell, 1991, 64
  http://rdf.ncbi.nlm.nih.gov/pubmed/1846319
• L W. Burrus, et.al., Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties., Experimental cell research, 1995, 220
  http://rdf.ncbi.nlm.nih.gov/pubmed/7556445
• Neil T. Sheehy, et.al., The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch., Development (Cambridge, England), 2010, 137
  http://rdf.ncbi.nlm.nih.gov/pubmed/21098571
• Jiang. Fu, et.al., Gpr177/mouse Wntless is essential for Wnt-mediated craniofacial and brain development., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21246653
• Ali G. Fenstermaker, et.al., Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21106844
• Minkui. Lin, et.al., Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth., Developmental dynamics : an official publication of the American Association of Anatomists, 2011, 240
  http://rdf.ncbi.nlm.nih.gov/pubmed/21246660
• B J. Gavin, et.al., Differential regulation of the Wnt gene family during pregnancy and lactation suggests a role in postnatal development of the mammary gland., Molecular and cellular biology, 1992, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/1373817
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• morphogenesis of an epithelium
  http://purl.obolibrary.org/obo/GO_0002009
• positive regulation of ossification
  http://purl.obolibrary.org/obo/GO_0045778
• positive regulation of macrophage activation
  http://purl.obolibrary.org/obo/GO_0043032
• cellular response to molecule of bacterial origin
  http://purl.obolibrary.org/obo/GO_0071219
• signal transduction
  http://purl.obolibrary.org/obo/GO_0007165
• axis elongation
  http://purl.obolibrary.org/obo/GO_0003401
• positive regulation of response to cytokine stimulus
  http://purl.obolibrary.org/obo/GO_0060760
• planar cell polarity pathway involved in neural tube closure
  http://purl.obolibrary.org/obo/GO_0090179
• transcription regulatory region DNA binding
  http://purl.obolibrary.org/obo/GO_0044212
• cell surface
  http://purl.obolibrary.org/obo/GO_0009986
• positive regulation of interleukin-8 secretion
  http://purl.obolibrary.org/obo/GO_2000484
• positive regulation of mesenchymal cell proliferation
  http://purl.obolibrary.org/obo/GO_0002053
• negative regulation of prostatic bud formation
  http://purl.obolibrary.org/obo/GO_0060686
• cochlea morphogenesis
  http://purl.obolibrary.org/obo/GO_0090103
• Wnt signaling pathway, planar cell polarity pathway
  http://purl.obolibrary.org/obo/GO_0060071
• vagina development
  http://purl.obolibrary.org/obo/GO_0060068
• activation of MAPK activity
  http://purl.obolibrary.org/obo/GO_0000187
• positive regulation of epithelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0050679
• positive regulation of angiogenesis
  http://purl.obolibrary.org/obo/GO_0045766
• positive regulation of protein catabolic process
  http://purl.obolibrary.org/obo/GO_0045732
• negative regulation of canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0090090
• cellular protein localization
  http://purl.obolibrary.org/obo/GO_0034613
• positive regulation of interferon-gamma production
  http://purl.obolibrary.org/obo/GO_0032729
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• neuron projection morphogenesis
  http://purl.obolibrary.org/obo/GO_0048812
• negative regulation of epithelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0050680
• face development
  http://purl.obolibrary.org/obo/GO_0060324
• positive regulation of cGMP metabolic process
  http://purl.obolibrary.org/obo/GO_0030825
• heart looping
  http://purl.obolibrary.org/obo/GO_0001947
• Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0016055
• cytokine activity
  http://purl.obolibrary.org/obo/GO_0005125
• wound healing
  http://purl.obolibrary.org/obo/GO_0042060
• axon guidance
  http://purl.obolibrary.org/obo/GO_0007411
• negative chemotaxis
  http://purl.obolibrary.org/obo/GO_0050919
• genitalia development
  http://purl.obolibrary.org/obo/GO_0048806
• anterior/posterior pattern specification
  http://purl.obolibrary.org/obo/GO_0009952
• establishment of planar polarity
  http://purl.obolibrary.org/obo/GO_0001736
• extracellular space
  http://purl.obolibrary.org/obo/GO_0005615
• hematopoietic stem cell proliferation
  http://purl.obolibrary.org/obo/GO_0071425
• JNK cascade
  http://purl.obolibrary.org/obo/GO_0007254
• positive regulation of peptidyl-threonine phosphorylation
  http://purl.obolibrary.org/obo/GO_0010800
• negative regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0000122
• activation of JUN kinase activity
  http://purl.obolibrary.org/obo/GO_0007257
• Wnt signaling pathway, calcium modulating pathway
  http://purl.obolibrary.org/obo/GO_0007223
• receptor tyrosine kinase-like orphan receptor binding
  http://purl.obolibrary.org/obo/GO_0005115
• positive regulation of JUN kinase activity
  http://purl.obolibrary.org/obo/GO_0043507
• anterior/posterior axis specification, embryo
  http://purl.obolibrary.org/obo/GO_0008595
• positive regulation of neuron projection development
  http://purl.obolibrary.org/obo/GO_0010976
• embryonic skeletal system development
  http://purl.obolibrary.org/obo/GO_0048706
• extracellular region
  http://purl.obolibrary.org/obo/GO_0005576
• positive regulation of macrophage cytokine production
  http://purl.obolibrary.org/obo/GO_0060907
• cell-cell signaling
  http://purl.obolibrary.org/obo/GO_0007267
• positive regulation of meiotic nuclear division
  http://purl.obolibrary.org/obo/GO_0045836
• inner ear morphogenesis
  http://purl.obolibrary.org/obo/GO_0042472
• primitive streak formation
  http://purl.obolibrary.org/obo/GO_0090009
• negative regulation of apoptotic process
  http://purl.obolibrary.org/obo/GO_0043066
• activation of protein kinase B activity
  http://purl.obolibrary.org/obo/GO_0032148
• negative regulation of BMP signaling pathway
  http://purl.obolibrary.org/obo/GO_0030514
• positive regulation of interleukin-6 production
  http://purl.obolibrary.org/obo/GO_0032755
• positive regulation of T cell chemotaxis
  http://purl.obolibrary.org/obo/GO_0010820
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cartilage development
  http://purl.obolibrary.org/obo/GO_0051216
• dorsal/ventral axis specification
  http://purl.obolibrary.org/obo/GO_0009950
• planar cell polarity pathway involved in pericardium morphogenesis
  http://purl.obolibrary.org/obo/GO_0061354
• canonical Wnt signaling pathway
  http://purl.obolibrary.org/obo/GO_0060070
• mesenchymal-epithelial cell signaling
  http://purl.obolibrary.org/obo/GO_0060638
• digestive tract morphogenesis
  http://purl.obolibrary.org/obo/GO_0048546
• pericardium morphogenesis
  http://purl.obolibrary.org/obo/GO_0003344
• positive regulation of cartilage development
  http://purl.obolibrary.org/obo/GO_0061036
• negative regulation of fat cell differentiation
  http://purl.obolibrary.org/obo/GO_0045599
• positive regulation of peptidyl-serine phosphorylation
  http://purl.obolibrary.org/obo/GO_0033138
• positive regulation of NF-kappaB transcription factor activity
  http://purl.obolibrary.org/obo/GO_0051092
• frizzled binding
  http://purl.obolibrary.org/obo/GO_0005109
• embryo development
  http://purl.obolibrary.org/obo/GO_0009790
• convergent extension involved in organogenesis
  http://purl.obolibrary.org/obo/GO_0060029
• embryonic digit morphogenesis
  http://purl.obolibrary.org/obo/GO_0042733
• regulation of branching involved in mammary gland duct morphogenesis
  http://purl.obolibrary.org/obo/GO_0060762
• somitogenesis
  http://purl.obolibrary.org/obo/GO_0001756
• urinary bladder development
  http://purl.obolibrary.org/obo/GO_0060157
• development of primary male sexual characteristics
  http://purl.obolibrary.org/obo/GO_0046546
• hindgut morphogenesis
  http://purl.obolibrary.org/obo/GO_0007442
• dopaminergic neuron differentiation
  http://purl.obolibrary.org/obo/GO_0071542
• negative regulation of synapse assembly
  http://purl.obolibrary.org/obo/GO_0051964
• negative regulation of axon extension involved in axon guidance
  http://purl.obolibrary.org/obo/GO_0048843
• olfactory bulb interneuron development
  http://purl.obolibrary.org/obo/GO_0021891
• negative regulation of mesenchymal cell proliferation
  http://purl.obolibrary.org/obo/GO_0072201
• cell migration
  http://purl.obolibrary.org/obo/GO_0016477
• negative regulation of fibroblast growth factor receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0040037
• extracellular matrix
  http://purl.obolibrary.org/obo/GO_0031012
• positive regulation of JNK cascade
  http://purl.obolibrary.org/obo/GO_0046330
• planar cell polarity pathway involved in cardiac muscle tissue morphogenesis
  http://purl.obolibrary.org/obo/GO_0061350
• planar cell polarity pathway involved in outflow tract morphogenesis
  http://purl.obolibrary.org/obo/GO_0061347
• male gonad development
  http://purl.obolibrary.org/obo/GO_0008584
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• membrane fraction
  http://purl.obolibrary.org/obo/GO_0005624
• positive regulation of chemokine biosynthetic process
  http://purl.obolibrary.org/obo/GO_0045080
• positive regulation of cell-cell adhesion
  http://purl.obolibrary.org/obo/GO_0022409
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• type B pancreatic cell development
  http://purl.obolibrary.org/obo/GO_0003323
• positive regulation of inflammatory response
  http://purl.obolibrary.org/obo/GO_0050729
• positive regulation of cytokine secretion involved in immune response
  http://purl.obolibrary.org/obo/GO_0002741
• positive regulation of endothelial cell proliferation
  http://purl.obolibrary.org/obo/GO_0001938
• epithelial cell proliferation involved in mammary gland duct elongation
  http://purl.obolibrary.org/obo/GO_0060750
• plasma membrane
  http://purl.obolibrary.org/obo/GO_0005886
• uterus development
  http://purl.obolibrary.org/obo/GO_0060065

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04916
• http://www.genome.jp/dbget-bin/www_bget?map05166
• http://www.genome.jp/dbget-bin/www_bget?map04340
• http://www.genome.jp/dbget-bin/www_bget?map04310
• http://www.genome.jp/dbget-bin/www_bget?map05200
• http://www.genome.jp/dbget-bin/www_bget?map05217

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Pathways in cancer
• Wnt signaling pathway
• Basal cell carcinoma
• HTLV-I infection
• Melanogenesis
• Hedgehog signaling pathway