CD12159

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12159

CD12159

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Rbpj

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• recombination signal binding protein for immunoglobulin kappa J region

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• recombining binding protein suppressor of hairless
• recombination signal binding protein for immunoglobulin kappa J region
• j kappa-recombination signal-binding protein

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• AI843960
• RBPjk
• RBP-J kappa
• RBP-J
• Rbpsuh
• CBF1
• Igkrsbp
• Igkjrb

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/19664

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• recombination signal binding protein for immunoglobulin kappa J region
  http://metadb.riken.jp/db/mgi_rdf/MGI:96522

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_001080927
• https://www.ncbi.nlm.nih.gov/nuccore/NM_009035
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001080928

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000039191

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.209292

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=147183

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• K A. Siminovitch, et.al., The human kappa deleting element and the mouse recombining segment share DNA sequence homology., Nucleic acids research, 1987, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/3104881
• M. Kawaichi, et.al., Genomic organization of mouse J kappa recombination signal binding protein (RBP-J kappa) gene., The Journal of biological chemistry, 1992, 267
  http://rdf.ncbi.nlm.nih.gov/pubmed/1740450
• Tadashi. Nomura, et.al., EphB signaling controls lineage plasticity of adult neural stem cell niche cells., Cell stem cell, 2010, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/21112567
• http://rdf.ncbi.nlm.nih.gov/pubmed/2556644
• Tao. Fu, et.al., Accelerated acute allograft rejection accompanied by enhanced T-cell proliferation and attenuated Treg function in RBP-J deficient mice., Molecular immunology, 2011, 48
  http://rdf.ncbi.nlm.nih.gov/pubmed/21168915
• Pablo. Gómez-del Arco, et.al., Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis., Immunity, 2010, 33
  http://rdf.ncbi.nlm.nih.gov/pubmed/21093322
• Jessica N. Copeland, et.al., Notch signaling regulates remodeling and vessel diameter in the extraembryonic yolk sac., BMC developmental biology, 2011, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/21352545
• Bernhard. Bielesz, et.al., Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20978353
• Y. Hamaguchi, et.al., Cloning and characterization of a protein binding to the J kappa recombination signal sequence of immunoglobulin genes., Advances in experimental medicine and biology, 1991, 292
  http://rdf.ncbi.nlm.nih.gov/pubmed/1950768
• S. Jarriault, et.al., Signalling downstream of activated mammalian Notch., Nature, 1995, 377
  http://rdf.ncbi.nlm.nih.gov/pubmed/7566092

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• regulation of gene expression
  http://purl.obolibrary.org/obo/GO_0010468
• negative regulation of cell differentiation
  http://purl.obolibrary.org/obo/GO_0045596
• cell fate commitment
  http://purl.obolibrary.org/obo/GO_0045165
• angiogenesis
  http://purl.obolibrary.org/obo/GO_0001525
• Notch signaling pathway
  http://purl.obolibrary.org/obo/GO_0007219
• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• negative regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045892
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• cell
  http://purl.obolibrary.org/obo/GO_0005623
• auditory receptor cell fate commitment
  http://purl.obolibrary.org/obo/GO_0009912
• RNA polymerase II core promoter sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0000979
• sequence-specific DNA binding
  http://purl.obolibrary.org/obo/GO_0043565
• sebaceous gland development
  http://purl.obolibrary.org/obo/GO_0048733
• pituitary gland development
  http://purl.obolibrary.org/obo/GO_0021983
• humoral immune response
  http://purl.obolibrary.org/obo/GO_0006959
• neuron differentiation
  http://purl.obolibrary.org/obo/GO_0030182
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• positive regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0045893
• defense response to bacterium
  http://purl.obolibrary.org/obo/GO_0042742
• sequence-specific DNA binding transcription factor activity
  http://purl.obolibrary.org/obo/GO_0003700
• interleukin-4 secretion
  http://purl.obolibrary.org/obo/GO_0072602
• positive regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008284
• epithelial to mesenchymal transition
  http://purl.obolibrary.org/obo/GO_0001837
• MAML1-RBP-Jkappa- ICN1 complex
  http://purl.obolibrary.org/obo/GO_0002193
• RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
  http://purl.obolibrary.org/obo/GO_0001077
• protein N-terminus binding
  http://purl.obolibrary.org/obo/GO_0047485
• B cell differentiation
  http://purl.obolibrary.org/obo/GO_0030183
• chromatin binding
  http://purl.obolibrary.org/obo/GO_0003682
• inflammatory response to antigenic stimulus
  http://purl.obolibrary.org/obo/GO_0002437
• DNA binding
  http://purl.obolibrary.org/obo/GO_0003677
• nucleolus
  http://purl.obolibrary.org/obo/GO_0005730
• negative regulation of cell proliferation
  http://purl.obolibrary.org/obo/GO_0008285
• transcription factor complex
  http://purl.obolibrary.org/obo/GO_0005667
• hair follicle maturation
  http://purl.obolibrary.org/obo/GO_0048820
• transcription factor binding
  http://purl.obolibrary.org/obo/GO_0008134
• hemopoiesis
  http://purl.obolibrary.org/obo/GO_0030097
• transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006351
• epidermal cell fate specification
  http://purl.obolibrary.org/obo/GO_0009957
• regulation of timing of cell differentiation
  http://purl.obolibrary.org/obo/GO_0048505
• positive regulation of transcription of Notch receptor target
  http://purl.obolibrary.org/obo/GO_0007221
• heart development
  http://purl.obolibrary.org/obo/GO_0007507
• keratinocyte differentiation
  http://purl.obolibrary.org/obo/GO_0030216
• regulation of transcription, DNA-templated
  http://purl.obolibrary.org/obo/GO_0006355

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04330

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Notch signaling pathway