CD12182

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12182

CD12182

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Pfn1

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• profilin 1

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• profilin 1
• profilin I
• profilin-1

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• actin binding protein
• Pfn

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/18643

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• profilin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97549

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_011072

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000018293

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.2647

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=176610

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• Anna-Karin. Johnsson, et.al., Microtubule-dependent localization of profilin I mRNA to actin polymerization sites in serum-stimulated cells., European journal of cell biology, 2010, 89
  http://rdf.ncbi.nlm.nih.gov/pubmed/20129697
• W. Witke, et.al., Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin., Cell, 1995, 81
  http://rdf.ncbi.nlm.nih.gov/pubmed/7720072
• D J. Kwiatkowski, et.al., Human profilin. Molecular cloning, sequence comparison, and chromosomal analysis., The Journal of biological chemistry, 1988, 263
  http://rdf.ncbi.nlm.nih.gov/pubmed/3356709
• Moustafa. Moustafa-Bayoumi, et.al., Vascular hypertrophy and hypertension caused by transgenic overexpression of profilin 1., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17942408
• Stéphane. Romero, et.al., How ATP hydrolysis controls filament assembly from profilin-actin: implication for formin processivity., The Journal of biological chemistry, 2007, 282
  http://rdf.ncbi.nlm.nih.gov/pubmed/17210567
• Ralph T. Böttcher, et.al., Profilin 1 is required for abscission during late cytokinesis of chondrocytes., The EMBO journal, 2009, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/19262563
• J S. Widada, et.al., Total coding sequence of profilin cDNA from Mus musculus macrophage., Nucleic acids research, 1989, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/2717414
• Giulio R. Romeo, et.al., Attenuated expression of profilin-1 confers protection from atherosclerosis in the LDL receptor null mouse., Circulation research, 2007, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/17615372
• G O. Gogstad, et.al., Characterization of the proteins of isolated human platelet alpha-granules. Evidence for a separate alpha-granule-pool of the glycoproteins IIb and IIIa., Biochimica et biophysica acta, 1981, 670
  http://rdf.ncbi.nlm.nih.gov/pubmed/6457647
• D J. Kwiatkowski, et.al., Identification of the functional profilin gene, its localization to chromosome subband 17p13.3, and demonstration of its deletion in some patients with Miller-Dieker syndrome., American journal of human genetics, 1990, 46
  http://rdf.ncbi.nlm.nih.gov/pubmed/1968707

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• nucleus
  http://purl.obolibrary.org/obo/GO_0005634
• protein binding
  http://purl.obolibrary.org/obo/GO_0005515
• positive regulation of stress fiber assembly
  http://purl.obolibrary.org/obo/GO_0051496
• actin binding
  http://purl.obolibrary.org/obo/GO_0003779
• regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0006357
• actin cytoskeleton
  http://purl.obolibrary.org/obo/GO_0015629
• cytoskeleton
  http://purl.obolibrary.org/obo/GO_0005856
• actin cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0030036
• positive regulation of viral transcription
  http://purl.obolibrary.org/obo/GO_0050434
• synaptosome
  http://purl.obolibrary.org/obo/GO_0019717
• proline-rich region binding
  http://purl.obolibrary.org/obo/GO_0070064
• cytoskeleton organization
  http://purl.obolibrary.org/obo/GO_0007010
• positive regulation of transcription from RNA polymerase II promoter
  http://purl.obolibrary.org/obo/GO_0045944
• phosphatidylinositol-4,5-bisphosphate binding
  http://purl.obolibrary.org/obo/GO_0005546
• regulation of actin polymerization or depolymerization
  http://purl.obolibrary.org/obo/GO_0008064
• cytoplasm
  http://purl.obolibrary.org/obo/GO_0005737
• sequestering of actin monomers
  http://purl.obolibrary.org/obo/GO_0042989
• synapse
  http://purl.obolibrary.org/obo/GO_0045202
• neural tube closure
  http://purl.obolibrary.org/obo/GO_0001843
• Rho GTPase binding
  http://purl.obolibrary.org/obo/GO_0017048
• receptor binding
  http://purl.obolibrary.org/obo/GO_0005102
• positive regulation of DNA metabolic process
  http://purl.obolibrary.org/obo/GO_0051054

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map05132
• http://www.genome.jp/dbget-bin/www_bget?map04810

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Regulation of actin cytoskeleton
• Salmonella infection