CD12247

http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12247

CD12247

トランスクリプトームデータ

遺伝子シンボル

http://metadb.riken.jp/db/BrainTx/geneSymbol

• Kcnk2

遺伝子名

http://metadb.riken.jp/db/BrainTx/geneName

• potassium channel, subfamily K, member 2

別名

http://metadb.riken.jp/db/BrainTx/alt_name

• TREK-1 K(+) channel subunit
• outward rectifying potassium channel protein TREK-1
• potassium channel subfamily K member 2
• two pore potassium channel TPKC1
• potassium channel, subfamily K, member 2

別名略称

http://metadb.riken.jp/db/BrainTx/alt_symbol

• TREK-1
• A430027H14Rik
• AI848635

NCBI遺伝子

http://metadb.riken.jp/db/BrainTx/NCBIGene

• https://www.ncbi.nlm.nih.gov/gene/16526

MGI遺伝子

http://metadb.riken.jp/db/BrainTx/mgiGene

• potassium channel, subfamily K, member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109366

BrainTx遺伝子

http://metadb.riken.jp/db/BrainTx/brainTxGene

脳発現画像

http://metadb.riken.jp/db/BrainTx/brainExpressionImage

時系列発現 (小脳)

http://metadb.riken.jp/db/BrainTx/brainExpression

脳発現特異性/組織別発現

http://metadb.riken.jp/db/BrainTx/brainSpecificity

BrainTx遺伝子カテゴリー

http://metadb.riken.jp/db/BrainTx/brainTxGeneCategory

NCBI Accession Number

http://metadb.riken.jp/db/BrainTx/NCBIAccessionNumber

• https://www.ncbi.nlm.nih.gov/nuccore/NM_010607
• https://www.ncbi.nlm.nih.gov/nuccore/NM_001159850

Ensembl 遺伝子

http://metadb.riken.jp/db/BrainTx/ensemblGene

• http://asia.ensembl.org/Mus_musculus/Gene/Summary?g=ENSMUSG00000037624

UniGene 遺伝子

http://metadb.riken.jp/db/BrainTx/uniGene

• https://www.ncbi.nlm.nih.gov/unigene/?term=Mm.33304

OMIM ID

http://metadb.riken.jp/db/BrainTx/omim

• https://www.omim.org/entry/603434?search=603434&highlight=603219

PubMed ID (PMID)

http://rdf.ncbi.nlm.nih.gov/pubmed/

• M. Fink, et.al., Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel., The EMBO journal, 1996, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/9003761
• Khodadad. Namiranian, et.al., Cerebrovascular responses in mice deficient in the potassium channel, TREK-1., American journal of physiology. Regulatory, integrative and comparative physiology, 2010, 299
  http://rdf.ncbi.nlm.nih.gov/pubmed/20357027
• H J. Meadows, et.al., Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel., Pflugers Archiv : European journal of physiology, 2000, 439
  http://rdf.ncbi.nlm.nih.gov/pubmed/10784345
• J M. Muller-Delp, The role of TREK-1 in cerebrovascular regulation remains elusive: focus on "Cerebrovascular responses in mice deficient in the potassium channel, TREK-1"., American journal of physiology. Regulatory, integrative and comparative physiology, 2010, 299
  http://rdf.ncbi.nlm.nih.gov/pubmed/20484697
• Jean. Mazella, et.al., Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design., PLoS biology, 2010, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/20405001
• Graciana. Diez-Roux, et.al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo., PLoS biology, 2011, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/21267068
• D. Bockenhauer, et.al., Genomic organization and chromosomal localization of the murine 2 P domain potassium channel gene Kcnk8: conservation of gene structure in 2 P domain potassium channels., Gene, 2000, 261
  http://rdf.ncbi.nlm.nih.gov/pubmed/11167025
• D. Kim, et.al., Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1)., Circulation research, 1998, 82
  http://rdf.ncbi.nlm.nih.gov/pubmed/9506712
• Emma L. Veale, et.al., Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain., The Journal of biological chemistry, 2010, 285
  http://rdf.ncbi.nlm.nih.gov/pubmed/20605797
• A J. Patel, et.al., Inhalational anesthetics activate two-pore-domain background K+ channels., Nature neuroscience, 1999, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/10321245

Gene Ontology

http://metadb.riken.jp/db/BrainTx/golink

• membrane
  http://purl.obolibrary.org/obo/GO_0016020
• potassium ion transport
  http://purl.obolibrary.org/obo/GO_0006813
• G-protein coupled receptor signaling pathway
  http://purl.obolibrary.org/obo/GO_0007186
• stabilization of membrane potential
  http://purl.obolibrary.org/obo/GO_0030322
• regulation of ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0034765
• ion channel activity
  http://purl.obolibrary.org/obo/GO_0005216
• potassium channel activity
  http://purl.obolibrary.org/obo/GO_0005267
• integral component of membrane
  http://purl.obolibrary.org/obo/GO_0016021
• voltage-gated potassium channel complex
  http://purl.obolibrary.org/obo/GO_0008076
• potassium ion transmembrane transport
  http://purl.obolibrary.org/obo/GO_0071805
• transport
  http://purl.obolibrary.org/obo/GO_0006810
• ion transport
  http://purl.obolibrary.org/obo/GO_0006811
• voltage-gated ion channel activity
  http://purl.obolibrary.org/obo/GO_0005244
• voltage-gated potassium channel activity
  http://purl.obolibrary.org/obo/GO_0005249

InterPro ID

http://metadb.riken.jp/db/BrainTx/interPro

KEGG Pathway ID

http://metadb.riken.jp/db/BrainTx/keggPathwayID

• http://www.genome.jp/dbget-bin/www_bget?map04971

KEGG Pathway 名称

http://metadb.riken.jp/db/BrainTx/keggPathwayName

• Gastric acid secretion